KEGG   DRUG: NomegestrolHelp
Entry
D07222                      Drug                                   

Name
Nomegestrol (USAN/INN)
Formula
C21H28O3
Exact mass
328.2038
Mol weight
328.4452
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01666  Progesterone receptor agonist
 DG02004  Progesterone
Remark
ATC code: G03DB04
Chemical structure group: DG00468
Efficacy
Ovulation inducing agent, Progesterone receptor agonist
Comment
Progestin, Pregnadiene derivative
Target
NR3C3 (PGR) [HSA:5241] [KO:K08556]
  Pathway
hsa04114  Oocyte meiosis
hsa04914  Progesterone-mediated oocyte maturation
hsa04915  Estrogen signaling pathway
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03D PROGESTOGENS
    G03DB Pregnadien derivatives
     G03DB04 Nomegestrol
      D07222  Nomegestrol (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C3 (PGR)
     D07222  Nomegestrol (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 58691-88-6
PubChem: 51091560
ChEMBL: CHEMBL2105722
LigandBox: D07222
NIKKAJI: J126.259I
LinkDB All DBs
KCF data Show

ATOM        24
            1   C1z C    29.2066  -17.0746
            2   C1y C    29.2066  -18.3988
            3   C1x C    31.5763  -18.3988
            4   C1x C    31.5763  -17.0746
            5   C1z C    30.3915  -16.3776
            6   C1x C    28.0218  -16.3776
            7   C1x C    26.8370  -17.0746
            8   C1y C    26.8370  -18.3988
            9   C1y C    28.0218  -19.0957
            10  C1y C    25.7219  -19.0957
            11  C2y C    25.7219  -20.4896
            12  C2y C    26.8370  -21.1169
            13  C2x C    28.0218  -20.4896
            14  C1x C    24.5371  -18.3988
            15  C1x C    23.3523  -19.0957
            16  C5x C    23.3523  -20.4896
            17  C2x C    24.5371  -21.1169
            18  C1a C    29.2066  -15.6807
            19  C5a C    30.3915  -14.9837
            20  C1a C    29.1843  -14.2868
            21  O1a O    31.6015  -15.6856
            22  C1a C    26.8193  -22.5107
            23  O5x O    22.1581  -21.2086
            24  O5a O    31.5969  -14.2877
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     1   6 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    9   2 1
            11    8  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 2
            15    9  13 1
            16   10  14 1
            17   14  15 1
            18   15  16 1
            19   16  17 1
            20   17  11 2
            21    1  18 1 #Up
            22    5  19 1 #Up
            23   19  20 1
            24    5  21 1 #Down
            25   12  22 1
            26   16  23 2
            27   19  24 2

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