KEGG   DRUG: Amoxicillin
Entry
D07452                      Drug                                   

Name
Amoxicillin (INN);
AMPC;
Amoxicillin (TN)
Formula
C16H19N3O5S
Exact mass
365.1045
Mol weight
365.4042
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
Remark
Same as: C06827
ATC code: J01CA04
Chemical structure group: DG00520
Product (DG00520): D00229<JP/US>
Product (mixture): D10246<US> D10519<JP> D10520<JP> D10774<JP> D10775<JP> D11858<US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA04 Amoxicillin
      D07452  Amoxicillin (INN)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D07452  Amoxicillin (INN)
Prodrugs [br08324.html]
 D07452
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00520  Amoxicillin
Other DBs
CAS: 26787-78-0
PubChem: 51091783
ChEBI: 2676
ChEMBL: CHEMBL1082
LigandBox: D07452
NIKKAJI: J3.165H
LinkDB
KCF data

ATOM        25
            1   C1y C    25.2700  -16.8000
            2   C5x C    25.2700  -18.2000
            3   N1y N    26.6700  -18.2000
            4   C1y C    26.6700  -16.8000
            5   C1y C    28.0000  -18.6200
            6   C1z C    28.8400  -17.5000
            7   S2x S    28.0000  -16.3800
            8   C1a C    29.8200  -18.4800
            9   C1a C    29.8200  -16.5200
            10  C6a C    28.4900  -20.0200
            11  O6a O    29.8900  -20.0200
            12  O6a O    27.6500  -21.1400
            13  N1b N    24.0800  -16.1000
            14  C5a C    22.8900  -16.8000
            15  O5x O    24.0800  -18.9000
            16  O5a O    22.8900  -18.2000
            17  C1c C    21.6300  -16.1000
            18  C8y C    20.4400  -16.8000
            19  N1a N    21.6300  -14.7000
            20  C8x C    19.2500  -16.1000
            21  C8x C    17.9900  -16.8000
            22  C8y C    17.9900  -18.2000
            23  C8x C    19.2500  -18.9000
            24  C8x C    20.4400  -18.2000
            25  O1a O    16.8000  -18.9000
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1
            27   22  25 1

» Japanese version   » Back

KEGG   DRUG: Amoxicillin
Entry
D00229                      Drug                                   

Name
Amoxicillin (USP);
Amoxicillin hydrate (JP18);
Amoxicilline (INN);
Amoxicillin trihydrate;
Amoxil (TN);
Dispermox (TN);
Pasetocin (TN)
Product
  Generic
AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (Asclemed USA), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Cambridge Therapeutics Technologies), AMOXIL (DIRECT RX), AMOXICILLIN (DIRECT RX), AMOXIL (DIRECT RX), AMOXICILLIN (DIRECT RX), AMOXICILLIN (DIRECT RX), AMOXICILLIN (DIRECT RX), AMOXICILLIN (DIRECTRX), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXIL (Direct_Rx), AMOXICILLIN (Hikma Pharmaceuticals USA), AMOXICILLIN (Hikma Pharmaceuticals USA), AMOXICILLIN (Lake Erie Medical DBA Quality Care Products LLC), AMOXICILLIN (Lake Erie Medical DBA Quality Care Products LLC), AMOXICILLIN (Lake Erie Medical DBA Quality Care Products LLC), AMOXICILLIN (Lake Erie Medical DBA Quality Care Products LLC), AMOXICILLIN (Lake Erie Medical DBA Quality Care Products LLC), AMOXICILLIN (Lake Erie Medical DBA Quality Care Products LLC), AMOXICILLIN (Neopharma), AMOXICILLIN (NorthStar Rx LLC), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PharmPak), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (QPharma), AMOXICILLIN (QPharma), AMOXICILLIN (QPharma), AMOXICILLIN (QPharma), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (Rising Health), AMOXICILLIN (Rising Health), AMOXICILLIN (Rising Health), AMOXICILLIN (Sandoz), AMOXICILLIN (Teva Pharmaceuticals USA), AMOXICILLIN (Teva Pharmaceuticals USA), AMOXICILLIN (Teva Pharmaceuticals USA), AMOXICILLIN (West-Ward Pharmaceuticals Corp), AMOXICILLIN (medsource pharmaceuticals)
Formula
C16H19N3O5S. 3H2O
Exact mass
419.1362
Mol weight
419.45
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
Remark
Therapeutic category: 6131
ATC code: J01CA04
Chemical structure group: DG00520
Product (DG00520): D00229<JP/US>
Product (mixture): D06485<JP/US> D08774<US> D10246<US> D10519<JP> D10520<JP> D10774<JP> D10775<JP> D11858<US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
  Disease
Gonorrhea [DS:H00315]
Helicobacter pylori infection [DS:H00320]
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA04 Amoxicillin
      D00229  Amoxicillin (USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Penicillins
   Amoxicillin
    D00229  Amoxicillin (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6131  Penicillins
     D00229  Amoxicillin (USP); Amoxicillin hydrate (JP18); Amoxicilline (INN)
Animal drugs in Japan [BR:br08331]
 97  Agents against pathogenic micro-organisms and parasites (except biological products and disinfectants)
  976  Antibiotic preparations
   9762  Antibiotic preparations for peroral and feed additive use
    D00229  Amoxicillin hydrate
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D00229  Amoxicillin (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00229  Amoxicillin hydrate
  D00229  Amoxicillin capsules
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00520  Amoxicillin
Other DBs
CAS: 61336-70-7
PubChem: 7847296
ChEBI: 51254
DrugBank: DB01060
LigandBox: D00229
NIKKAJI: J1.892.001H
LinkDB
KCF data

ATOM        28
            1   C1y C    24.5313  -17.0264
            2   C5x C    24.5313  -18.4300
            3   N1y N    25.9349  -18.4300
            4   C1y C    25.9349  -17.0264
            5   C1y C    27.2683  -18.8510
            6   C1z C    28.1103  -17.7281
            7   S2x S    27.2683  -16.6053
            8   C1a C    29.0929  -18.7107
            9   C1a C    29.0929  -16.7456
            10  C6a C    27.7595  -20.1844
            11  O6a O    29.1630  -20.1844
            12  O6a O    26.9173  -21.3072
            13  N1b N    23.3383  -16.3246
            14  C5a C    22.1452  -17.0264
            15  O5x O    23.3383  -19.1317
            16  O5a O    22.1452  -18.4300
            17  C1c C    20.9268  -16.3295
            18  C8y C    19.7355  -17.0241
            19  N1a N    20.9268  -14.9295
            20  C8x C    18.5230  -16.3241
            21  C8x C    17.3106  -17.0241
            22  C8y C    17.3106  -18.4241
            23  C8x C    18.5230  -19.1241
            24  C8x C    19.7355  -18.4241
            25  O1a O    16.0891  -19.1295
            26  O0  O    34.0923  -18.2711
            27  O0  O    34.0923  -18.2711
            28  O0  O    34.0923  -18.2711
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1
            27   22  25 1
BRACKET     1    32.1300  -19.1800   32.1300  -17.3600
            1    34.5800  -17.3600   34.5800  -19.1800
            1  3
 ORIGINAL  1   27
 REPEAT    1   28  29

» Japanese version   » Back

KEGG   DRUG: Amoxicillin sodium
Entry
D02925                      Drug                                   

Name
Amoxicillin sodium (USAN)
Formula
C16H18N3O5S. Na
Exact mass
387.0865
Mol weight
387.386
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
Remark
ATC code: J01CA04
Chemical structure group: DG00520
Product (DG00520): D00229<JP/US>
Product (mixture): D06485<JP/US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA04 Amoxicillin
      D02925  Amoxicillin sodium (USAN)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D02925  Amoxicillin sodium (USAN)
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00520  Amoxicillin
Other DBs
CAS: 34642-77-8
PubChem: 17397082
ChEMBL: CHEMBL2105950
DrugBank: DB01060
LigandBox: D02925
NIKKAJI: J250.938E
LinkDB
KCF data

ATOM        26
            1   C1y C    25.9451  -14.8660
            2   C5x C    25.9451  -16.2704
            3   N1y N    27.3495  -16.2704
            4   C1y C    27.3495  -14.8660
            5   C1y C    28.6836  -16.6916
            6   C1z C    29.5261  -15.5681
            7   S2x S    28.6836  -14.4446
            8   C1a C    30.5093  -16.5512
            9   C1a C    30.5093  -14.5850
            10  C6a C    29.1751  -18.0257
            11  O6a O    30.5794  -18.0257 #-
            12  O6a O    28.3324  -19.1492
            13  N1b N    24.7514  -14.1638
            14  C5a C    23.5577  -14.8660
            15  O5x O    24.7514  -16.9725
            16  O5a O    23.5577  -16.2704
            17  C1c C    22.3386  -14.1687
            18  C8y C    21.1466  -14.8637
            19  N1a N    22.3386  -12.7679
            20  C8x C    19.9334  -14.1633
            21  C8x C    18.7203  -14.8637
            22  C8y C    18.7203  -16.2645
            23  C8x C    19.9334  -16.9649
            24  C8x C    21.1466  -16.2645
            25  O1a O    17.4981  -16.9703
            26  Z   Na   32.2700  -18.1300 #+
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1
            27   22  25 1

» Japanese version   » Back

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