| Entry |
|
|---|
| Name |
Befunolol (INN) |
|---|
| Formula |
C16H21NO4
|
|---|
| Exact mass |
291.1471
|
|---|
| Mol weight |
291.34
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01ED Beta blocking agents
S01ED06 Befunolol
D07496 Befunolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01138 Befunolol
D07496 Befunolol
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01138 Befunolol
D07496 Befunolol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D07496 Befunolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01138 Befunolol
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01138 Befunolol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 O2a O 20.0200 -19.4600
2 C1b C 21.2800 -18.7600
3 C1c C 22.4700 -19.4600
4 C1b C 23.6600 -18.7600
5 N1b N 24.9200 -19.4600
6 C1c C 26.1100 -18.7600
7 C1a C 27.3000 -19.4600
8 C1a C 26.1100 -17.3600
9 O1a O 22.4700 -20.8600
10 C8y C 20.0200 -20.8600
11 C8y C 18.8300 -21.5600
12 C8y C 18.8300 -22.9600
13 C8x C 20.0200 -23.6600
14 C8x C 21.2100 -22.9600
15 C8x C 21.2100 -21.5600
16 O2x O 17.5000 -21.1400
17 C8y C 16.6600 -22.2600
18 C8x C 17.5000 -23.3800
19 C5a C 15.2600 -22.2600
20 C1a C 14.5600 -21.0700
21 O5a O 14.5600 -23.4500
BOND 22
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 6 8 1
8 3 9 1
9 1 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 13 14 1
14 14 15 2
15 10 15 1
16 11 16 1
17 16 17 1
18 17 18 2
19 12 18 1
20 17 19 1
21 19 20 1
22 19 21 2
|
|---|
