KEGG   DRUG: AdomiparinHelp
Entry
D07510                      Drug                                   

Name
Adomiparin (USAN);
Semuloparin (USAN);
Heparin (BAN);
Enoxaparin;
Bemiparin;
Parnaparin;
Nadroparin;
Heparin (TN)
Formula
(C26H40N2O36S5)n
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01709  Heparin anticoagulant
 DG01950  Antithrombotic agent
  DG01709  Heparin anticoagulant
Remark
Same as: C00374
ATC code: B01AB01 B01AB12 C05BA03 S01XA14
Chemical structure group: DG00150
Product (DG00150): D02112<JP/US> D04427<JP> D03674<JP/US> D04977<JP> D03337<JP> D03353<JP/US>
Efficacy
Anticoagulant, Antithrombin III activator, Platelet aggregation inhibitor
Comment
Low molecular weight heparin (LMWH)
Target
SERPINC1 (AT3) [HSA:462] [KO:K03911]
  Pathway
hsa04610  Complement and coagulation cascades
Interaction
Drug interaction
Structure map
map07049  Antithrombosis agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AB Heparin group
     B01AB01 Heparin
      D07510  Adomiparin (USAN)
     B01AB12 Bemiparin
      D07510  Adomiparin (USAN)
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05B ANTIVARICOSE THERAPY
    C05BA Heparins or heparinoids for topical use
     C05BA03 Heparin
      D07510  Adomiparin (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01X OTHER OPHTHALMOLOGICALS
    S01XA Other ophthalmologicals
     S01XA14 Heparin
      D07510  Adomiparin (USAN)
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Immune system
   Complement and coagulation
    SERPINC1 (AT3)
     D07510  Adomiparin (USAN)
BRITE hierarchy
Other DBs
CAS: 9005-49-6
PubChem: 96024437
ChEBI: 28304
NIKKAJI: J293.322E
LinkDB All DBs
KCF data Show

ATOM        71
            1   C1y C    20.6500  -19.0400
            2   C1y C    21.7700  -19.6700
            3   C1y C    20.6500  -17.7100
            4   O2a O    19.0400  -19.9500
            5   C1y C    22.8900  -19.0400
            6   O2a O    21.7700  -21.0000
            7   O2x O    21.7700  -17.0800
            8   C1b C    19.4600  -17.0800
            9   C1y C    17.3600  -20.8600
            10  C1y C    22.8900  -17.7100
            11  N1b N    23.9400  -20.2300
            12  O1a O    18.3400  -17.7100
            13  C1y C    17.3600  -22.1900
            14  O2x O    16.2400  -20.2300
            15  O2a O    24.5000  -16.8000
            16  S4a S    25.9000  -20.2300
            17  C1y C    16.2400  -22.8900
            18  O2a O    18.9000  -23.8000
            19  C1y C    15.1200  -20.8600
            20  C1y C    26.1800  -15.8200
            21  O1d O    25.9000  -21.5600
            22  O1d O    25.9000  -18.9000
            23  O1d O    27.2300  -20.2300
            24  C1y C    15.1200  -22.1900
            25  O1a O    16.2400  -24.1500
            26  C6a C    14.0000  -20.2300
            27  C1y C    26.1800  -14.4900
            28  C1y C    27.3000  -16.5200
            29  O1a O    13.9300  -22.8900
            30  O6a O    12.8100  -20.8600
            31  O6a O    14.0000  -18.9000
            32  O2x O    27.3000  -13.8600
            33  C6a C    24.9900  -13.8600
            34  C1y C    28.4200  -15.8200
            35  O1a O    27.3000  -17.7800
            36  Z   *    11.1300  -22.8200
            37  C1y C    28.4200  -14.4900
            38  O6a O    23.8700  -14.4900
            39  O6a O    24.9900  -12.5300
            40  O2a O    30.8700  -17.2900
            41  O2a O    30.0300  -13.5800
            42  C1y C    31.7100  -12.6000
            43  C1y C    31.7100  -11.3400
            44  C1y C    32.8300  -13.3000
            45  O2x O    32.8300  -10.6400
            46  C1b C    30.5200  -10.6400
            47  C1y C    33.9500  -12.6000
            48  O1a O    32.8300  -14.6300
            49  C1x C    33.9500  -11.3400
            50  O2a O    29.2600  -10.6400
            51  N1b N    35.9800  -13.5800
            52  Z   *    36.4000   -9.9400
            53  S4a S    27.9300  -10.6400
            54  C5a C    35.9800  -14.9100
            55  O1d O    27.9300  -11.9700
            56  O1d O    27.9300   -9.3100
            57  O1d O    26.6000  -10.6400
            58  C1a C    37.1700  -15.5400
            59  O5a O    34.8600  -15.5400
            60  S4a S    18.9000  -25.2000
            61  O1d O    18.9000  -26.6000
            62  O1d O    20.3000  -25.2000
            63  O1d O    17.5000  -25.2000
            64  S4a S    21.7700  -22.4000
            65  O1d O    21.7700  -23.8000
            66  O1d O    23.1700  -22.4000
            67  O1d O    20.3700  -22.4000
            68  S4a S    30.8700  -18.6900
            69  O1d O    30.8700  -20.0900
            70  O1d O    32.2700  -18.6900
            71  O1d O    29.4700  -18.6900
BOND        74
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 1 #Up
            8     9   4 1 #Up
            9     5  10 1
            10    5  11 1 #Down
            11    8  12 1
            12    9  13 1
            13    9  14 1
            14   10  15 1 #Down
            15   11  16 1
            16   13  17 1
            17   13  18 1 #Down
            18   14  19 1
            19   20  15 1 #Down
            20   16  21 1
            21   16  22 2
            22   16  23 2
            23   17  24 1
            24   17  25 1 #Up
            25   19  26 1 #Down
            26   20  27 1
            27   20  28 1
            28   24  29 1 #Down
            29   26  30 1
            30   26  31 2
            31   27  32 1
            32   27  33 1 #Up
            33   28  34 1
            34   28  35 1 #Up
            35   29  36 1
            36   32  37 1
            37   33  38 1
            38   33  39 2
            39   34  40 1 #Down
            40   37  41 1 #Up
            41   42  41 1 #Down
            42   42  43 1
            43   42  44 1
            44   43  45 1
            45   43  46 1 #Up
            46   44  47 1
            47   44  48 1 #Up
            48   45  49 1
            49   46  50 1
            50   47  51 1 #Down
            51   49  52 1
            52   50  53 1
            53   51  54 1
            54   53  55 1
            55   53  56 2
            56   53  57 2
            57   54  58 1
            58   54  59 2
            59    7  10 1
            60   19  24 1
            61   34  37 1
            62   47  49 1
            63   18  60 1
            64   60  61 2
            65   60  62 2
            66   60  63 1
            67    6  64 1
            68   64  65 2
            69   64  66 2
            70   64  67 1
            71   40  68 1
            72   68  69 2
            73   68  70 2
            74   68  71 1
BRACKET     1    12.3900  -23.4500   12.3900  -22.1200
            1    35.0000   -9.9400   35.0000  -11.2700
            1  n
 ORIGINAL  1    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16
            1   17  18  19  20  21  22  23  24  25  26  27  28  29  30  31  32
            1   33  34  35  37  38  39  40  41  42  43  44  45  46  47  48  49
            1   50  51  53  54  55  56  57  58  59  60  61  62  63  64  65  66
            1   67  68  69  70  71
 REPEAT    1

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