Homo sapiens (human): 462
Help
Entry
462 CDS
T01001
Symbol
SERPINC1, AT3, AT3D, ATIII, ATIII-R2, ATIII-T1, ATIII-T2, THPH7
Name
(RefSeq) serpin family C member 1
KO
K03911
antithrombin III
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
Disease
H00223
Inherited thrombophilia
H01381
Antithrombin III deficiency
H01723
Deep vein thrombosis
Drug target
Anticoagulant heparin:
D02956
Dalteparin:
D03353
<JP/US>
Danaparoid:
D03644
<JP>
Delparantag pentahydrochloride:
D10418
Enoxaparin:
D03674
<JP/US>
Fitusiran sodium:
D11810
Fondaparinux:
D01844
<JP/US>
Heparin (
DG00150
):
D02112
<JP/US>
D02980
D03673
D04427
<JP>
D07510
Parnaparin:
D04977
<JP>
Reviparin:
D03337
Sulodexide:
D08547
Tinzaparin:
D06398
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
462 (SERPINC1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
462 (SERPINC1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
462 (SERPINC1)
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
462 (SERPINC1)
Peptidases and inhibitors [BR:
hsa01002
]
Peptidase inhibitors
Family I4: serpin family
462 (SERPINC1)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other cancer cells
462 (SERPINC1)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Coagulation and fibrinolysis
462 (SERPINC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Serpin
Motif
Other DBs
NCBI-GeneID:
462
NCBI-ProteinID:
NP_000479
OMIM:
107300
HGNC:
775
Ensembl:
ENSG00000117601
Vega:
OTTHUMG00000037276
Pharos:
P01008
(Tclin)
UniProt:
P01008
A0A024R944
Structure
PDB
LinkDB
All DBs
Position
1:complement(173903800..173917327)
Genome browser
AA seq
464 aa
AA seq
DB search
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEK
KATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFA
MTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFG
DKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAIN
ELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQ
VLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDG
FSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAV
VIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgtattccaatgtgataggaactgtaacctctggaaaaaggaaggtttatcttttgtcc
ttgctgctcattggcttctgggactgcgtgacctgtcacgggagccctgtggacatctgc
acagccaagccgcgggacattcccatgaatcccatgtgcatttaccgctccccggagaag
aaggcaactgaggatgagggctcagaacagaagatcccggaggccaccaaccggcgtgtc
tgggaactgtccaaggccaattcccgctttgctaccactttctatcagcacctggcagat
tccaagaatgacaatgataacattttcctgtcacccctgagtatctccacggcttttgct
atgaccaagctgggtgcctgtaatgacaccctccagcaactgatggaggtatttaagttt
gacaccatatctgagaaaacatctgatcagatccacttcttctttgccaaactgaactgc
cgactctatcgaaaagccaacaaatcctccaagttagtatcagccaatcgcctttttgga
gacaaatcccttaccttcaatgagacctaccaggacatcagtgagttggtatatggagcc
aagctccagcccctggacttcaaggaaaatgcagagcaatccagagcggccatcaacaaa
tgggtgtccaataagaccgaaggccgaatcaccgatgtcattccctcggaagccatcaat
gagctcactgttctggtgctggttaacaccatttacttcaagggcctgtggaagtcaaag
ttcagccctgagaacacaaggaaggaactgttctacaaggctgatggagagtcgtgttca
gcatctatgatgtaccaggaaggcaagttccgttatcggcgcgtggctgaaggcacccag
gtgcttgagttgcccttcaaaggtgatgacatcaccatggtcctcatcttgcccaagcct
gagaagagcctggccaaggtagagaaggaactcaccccagaggtgctgcaagagtggctg
gatgaattggaggagatgatgctggtggtccacatgccccgcttccgcattgaggacggc
ttcagtttgaaggagcagctgcaagacatgggccttgtcgatctgttcagccctgaaaag
tccaaactcccaggtattgttgcagaaggccgagatgacctctatgtctcagatgcattc
cataaggcatttcttgaggtaaatgaagaaggcagtgaagcagctgcaagtaccgctgtt
gtgattgctggccgttcgctaaaccccaacagggtgactttcaaggccaacaggcctttc
ctggtttttataagagaagttcctctgaacactattatcttcatgggcagagtagccaac
ccttgtgttaagtaa
DBGET
integrated database retrieval system
