KEGG   DRUG: BupranololHelp
Entry
D07590                      Drug                                   

Name
Bupranolol (INN)
Formula
C14H22ClNO2
Exact mass
271.1339
Mol weight
271.783
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Remark
ATC code: C07AA19
Chemical structure group: DG00311
Efficacy
Antiglaucoma, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA19 Bupranolol
      D07590  Bupranolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D07590  Bupranolol (INN)
BRITE hierarchy
Other DBs
CAS: 14556-46-8
PubChem: 51091902
ChEMBL: CHEMBL305380
LigandBox: D07590
NIKKAJI: J8.508A
LinkDB All DBs
KCF data Show

ATOM        18
            1   O2a O    18.5500  -15.6800
            2   C1b C    19.7400  -14.9800
            3   C1c C    21.0000  -15.6800
            4   C1b C    22.1900  -14.9800
            5   O1a O    21.0000  -17.0800
            6   N1b N    23.3800  -15.6800
            7   C1d C    24.6400  -14.9800
            8   C1a C    25.8300  -15.7500
            9   C1a C    24.6400  -13.5800
            10  C1a C    25.9000  -14.3500
            11  C8y C    18.5500  -17.0800
            12  C8y C    17.3600  -17.7800
            13  C8x C    17.3600  -19.1800
            14  C8x C    18.5500  -19.8800
            15  C8y C    19.7400  -19.2500
            16  C8x C    19.7400  -17.7800
            17  X   Cl   16.1700  -17.0800
            18  C1a C    21.0000  -19.9500
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     3   5 1
            5     4   6 1
            6     6   7 1
            7     7   8 1
            8     7   9 1
            9     7  10 1
            10    1  11 1
            11   11  12 2
            12   12  13 1
            13   13  14 2
            14   14  15 1
            15   15  16 2
            16   11  16 1
            17   12  17 1
            18   15  18 1

» Japanese version   » Back

DBGET integrated database retrieval system