| Entry |
|
|---|
| Name |
Chlorprothixene citrate;
Truxal (TN) |
|---|
| Formula |
C18H18ClNS. C6H8O7
|
|---|
| Exact mass |
507.1119
|
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| Mol weight |
507.98
|
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| Structure |
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| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Neuroleptic, Dopamine receptor antagonist |
|---|
| Comment |
Thioxanthene derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AF Thioxanthene derivatives
N05AF03 Chlorprothixene
D07687 Chlorprothixene citrate
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00894 Chlorprothixene
D07687 Chlorprothixene citrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D07687 Chlorprothixene citrate
DRD2
D07687 Chlorprothixene citrate
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00894 Chlorprothixene
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 34
1 C8x C 5.0039 -11.0921
2 C8x C 5.0039 -12.4945
3 C8x C 6.1959 -13.2658
4 C8y C 7.4581 -12.4945
5 C8y C 7.4581 -11.0921
6 C8x C 6.1959 -10.3909
7 S2x S 8.6501 -13.2658
8 C8y C 9.9123 -12.4945
9 C8y C 9.9123 -11.0921
10 C8y C 8.6501 -10.3909
11 C8x C 11.0342 -13.2658
12 C8x C 12.2262 -12.4945
13 C8y C 12.2262 -11.0921
14 C8x C 11.0342 -10.3909
15 C2b C 8.6501 -8.9886
16 C1b C 9.9123 -8.2874
17 C1b C 11.0342 -8.9886
18 N1c N 12.2262 -8.2874
19 C1a C 13.4182 -8.9886
20 C1a C 12.2262 -6.9551
21 X Cl 13.4883 -10.3909
22 C1d C 20.2300 -9.8700
23 C1b C 19.0400 -10.5700
24 C1b C 21.4200 -10.5700
25 C6a C 20.9300 -8.6800
26 O1a O 19.5300 -8.6800
27 C6a C 17.8500 -9.9400
28 C6a C 21.4200 -11.9700
29 O6a O 20.2300 -7.4900
30 O6a O 22.3300 -8.6800
31 O6a O 16.5900 -10.6400
32 O6a O 17.8500 -8.5400
33 O6a O 22.6800 -12.6700
34 O6a O 20.2300 -12.6700
BOND 35
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 2
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 18 20 1
23 13 21 1
24 22 23 1
25 22 24 1
26 22 25 1
27 22 26 1
28 23 27 1
29 24 28 1
30 25 29 1
31 25 30 2
32 27 31 1
33 27 32 2
34 28 33 1
35 28 34 2
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