| Entry |
|
|---|
| Name |
Flupentixol decanoate;
Fluanxol depot (TN) |
|---|
| Formula |
C33H43F3N2O2S
|
|---|
| Exact mass |
588.2997
|
|---|
| Mol weight |
588.77
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Neuroleptic, Dopamine receptor antagonist |
|---|
| Comment |
Thioxanthene derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AF Thioxanthene derivatives
N05AF01 Flupentixol
D07976 Flupentixol decanoate
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00893 Flupentixol
D07976 Flupentixol decanoate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D07976 Flupentixol decanoate
DRD2
D07976 Flupentixol decanoate
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00893 Flupentixol
|
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| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 41
1 C8x C 18.1300 -20.3700
2 C8x C 18.1300 -21.7700
3 C8x C 19.3900 -22.4700
4 C8x C 19.3900 -19.6700
5 C8y C 20.5100 -20.3700
6 C8y C 20.5100 -21.7700
7 S2x S 21.7700 -22.4700
8 C8y C 21.7700 -19.6700
9 C8y C 22.9600 -20.3700
10 C8y C 22.9600 -21.7700
11 C8x C 24.1500 -22.4700
12 C8x C 25.4100 -21.7700
13 C8y C 25.4100 -20.3700
14 C8x C 24.1500 -19.6700
15 C2b C 21.7700 -18.2700
16 C1b C 23.0300 -17.5700
17 C1b C 23.0300 -16.1700
18 N1y N 24.2200 -15.4700
19 C1x C 25.4100 -16.1700
20 C1x C 26.6000 -15.4700
21 N1y N 26.6000 -14.0700
22 C1x C 25.4100 -13.3700
23 C1x C 24.2200 -14.0700
24 C1b C 27.8600 -13.3700
25 C1b C 29.0500 -14.0700
26 O7a O 30.2400 -13.3700
27 C1d C 26.6700 -19.6700
28 X F 27.8600 -18.9700
29 X F 25.9700 -18.4800
30 X F 27.3700 -20.8600
31 C7a C 31.4581 -14.0601
32 C1b C 32.6395 -13.3650
33 O6a O 31.4698 -15.4694
34 C1b C 33.8449 -14.0480
35 C1b C 35.0161 -13.3591
36 C1b C 36.2265 -14.0451
37 C1b C 37.4466 -13.3271
38 C1b C 38.6557 -14.0116
39 C1b C 39.8554 -13.3052
40 C1b C 41.0522 -13.9828
41 C1a C 42.2272 -13.2911
BOND 44
1 8 5 1
2 1 2 1
3 2 3 2
4 3 6 1
5 9 10 2
6 10 11 1
7 11 12 2
8 12 13 1
9 13 14 2
10 14 9 1
11 5 4 1
12 8 15 2
13 4 1 2
14 5 6 2
15 6 7 1
16 7 10 1
17 9 8 1
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 18 23 1
27 21 24 1
28 24 25 1
29 25 26 1
30 13 27 1
31 27 28 1
32 27 29 1
33 27 30 1
34 26 31 1
35 31 32 1
36 31 33 2
37 32 34 1
38 34 35 1
39 35 36 1
40 36 37 1
41 37 38 1
42 38 39 1
43 39 40 1
44 40 41 1
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