| Entry |
|
|---|
| Name |
Hydroxyprogesterone (INN) |
|---|
| Formula |
C21H30O3
|
|---|
| Exact mass |
330.2195
|
|---|
| Mol weight |
330.46
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (DG00467): | D00949<JP/US> |
|
|---|
| Efficacy |
Menstruation disorder agent, Progesterone receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03D PROGESTOGENS
G03DA Pregnen (4) derivatives
G03DA03 Hydroxyprogesterone
D08052 Hydroxyprogesterone (INN)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00467 Hydroxyprogesterone
D08052 Hydroxyprogesterone
DG01666 Progesterone receptor agonist
DG00467 Hydroxyprogesterone
D08052 Hydroxyprogesterone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D08052 Hydroxyprogesterone (INN)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00467 Hydroxyprogesterone
DG01666 Progesterone receptor agonist
DG00467 Hydroxyprogesterone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C1x C 22.6100 -19.8100
2 C5x C 22.6100 -21.2100
3 C2x C 23.8000 -21.8400
4 C2y C 24.9900 -21.2100
5 C1z C 24.9900 -19.8100
6 C1x C 23.8000 -19.1100
7 C1x C 26.1800 -21.8400
8 C1x C 27.4400 -21.2100
9 C1y C 27.4400 -19.8100
10 C1y C 26.1800 -19.1100
11 C1y C 28.6300 -19.1100
12 C1z C 28.6300 -17.7100
13 C1x C 27.4400 -17.0100
14 C1x C 26.1800 -17.7100
15 O5x O 21.4200 -21.8400
16 C1a C 24.9900 -18.4100
17 C1a C 28.6300 -16.3100
18 C1x C 31.0549 -19.1100
19 C1x C 31.0549 -17.7100
20 C1z C 29.8424 -17.0100
21 C5a C 29.8424 -15.6102
22 O5a O 28.6132 -14.9003
23 C1a C 31.0380 -14.9198
24 O1a O 31.0379 -16.3196
BOND 27
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 2 15 2
18 5 16 1 #Up
19 12 17 1 #Up
20 11 18 1
21 18 19 1
22 19 20 1
23 12 20 1
24 20 21 1 #Up
25 21 22 2
26 21 23 1
27 20 24 1 #Down
|
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