| Entry |
|
|---|
| Name |
Hydroxyzine (INN);
Marex (TN) |
|---|
| Formula |
C21H27ClN2O2
|
|---|
| Exact mass |
374.1761
|
|---|
| Mol weight |
374.90
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
| Product (DG00912): | D00672<JP/US> D01096<JP/US> |
|
|---|
| Efficacy |
Tranquilizer, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05B ANXIOLYTICS
N05BB Diphenylmethane derivatives
N05BB01 Hydroxyzine
D08054 Hydroxyzine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00912 Hydroxyzine
D08054 Hydroxyzine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D08054 Hydroxyzine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00912 Hydroxyzine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C8x C 21.0700 -18.2700
2 C8y C 21.0700 -19.6700
3 C8x C 22.2600 -20.3700
4 C8x C 23.5200 -19.6700
5 C8y C 23.5200 -18.2700
6 C8x C 22.2600 -17.5700
7 C8x C 25.9000 -19.6700
8 C8y C 25.9000 -18.2700
9 C1c C 24.7100 -17.5700
10 N1y N 24.7100 -16.1700
11 C1x C 25.9000 -15.4700
12 C1x C 25.9000 -14.0700
13 N1y N 24.7100 -13.3700
14 C1x C 23.5200 -14.0700
15 C1x C 23.5200 -15.4700
16 C8x C 27.1600 -20.3700
17 C8x C 28.3500 -19.6700
18 C8x C 28.3500 -18.2700
19 C8x C 27.1600 -17.5700
20 X Cl 19.8800 -20.3700
21 C1b C 24.7100 -11.9700
22 C1b C 25.9000 -11.2700
23 O2a O 27.0900 -11.9700
24 C1b C 28.2800 -11.2700
25 C1b C 29.4700 -11.9700
26 O1a O 30.6600 -11.2700
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 10 15 1
17 7 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 8 19 2
22 2 20 1
23 13 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 24 25 1
28 25 26 1
|
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