KEGG   DRUG: MosaprideHelp
Entry
D08236                      Drug                                   

Name
Mosapride (INN);
Mosart (TN)
Formula
C21H25ClFN3O3
Exact mass
421.1568
Mol weight
421.8929
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Gastrointestinal agent
 DG01763  Propulsive
Enzyme substrate
 DG01633  CYP3A substrate
Remark
Chemical structure group: DG01285
Product (DG01285): D01994<JP>
Efficacy
Prokinetic, Serotonin receptor agonist
Target
HTR4 [HSA:3360] [KO:K04160]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
map07211  Serotonin receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    HTR4
     D08236  Mosapride (INN)
BRITE hierarchy
Other DBs
CAS: 112885-41-3
PubChem: 96024924
ChEMBL: CHEMBL60889
LigandBox: D08236
NIKKAJI: J245.710E
LinkDB All DBs
KCF data Show

ATOM        29
            1   C8y C    11.3400  -16.1700
            2   C8y C    11.3400  -14.7700
            3   C8x C    12.6000  -14.0700
            4   C8y C    13.7900  -14.7700
            5   C8y C    13.7900  -16.1700
            6   C8x C    12.6000  -16.8700
            7   C5a C    14.9800  -16.8700
            8   N1b N    16.2400  -16.1700
            9   C1b C    17.4300  -16.8700
            10  C1y C    18.6200  -16.1700
            11  O2x O    18.6200  -14.7700
            12  C1x C    19.8800  -14.0700
            13  C1x C    21.0700  -14.7700
            14  N1y N    21.0700  -16.1700
            15  C1x C    19.8800  -16.8700
            16  O2a O    14.9800  -14.0700
            17  C1b C    16.2400  -14.7700
            18  C1a C    17.4300  -14.0700
            19  X   Cl   10.1500  -16.8700
            20  N1a N    10.1500  -14.0700
            21  O5a O    14.9800  -18.2700
            22  C1b C    22.2600  -16.8700
            23  C8y C    23.5200  -16.1700
            24  C8x C    23.5200  -14.7700
            25  C8x C    24.7100  -14.0700
            26  C8y C    25.9000  -14.7700
            27  C8x C    25.9000  -16.1700
            28  C8x C    24.7100  -16.8700
            29  X   F    27.1600  -14.0700
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   10  15 1
            17    4  16 1
            18   16  17 1
            19   17  18 1
            20    1  19 1
            21    2  20 1
            22    7  21 2
            23   14  22 1
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28   26  27 1
            29   27  28 2
            30   23  28 1
            31   26  29 1

» Japanese version   » Back

DBGET integrated database retrieval system