KEGG   DRUG: Nomegestrol acetateHelp
Entry
D08281                      Drug                                   

Name
Nomegestrol acetate (USAN);
Lutenyl (TN)
Formula
C23H30O4
Exact mass
370.2144
Mol weight
370.4819
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01666  Progesterone receptor agonist
 DG02004  Progesterone
Remark
ATC code: G03DB04
Chemical structure group: DG00468
Efficacy
Contraceptive, Progesterone receptor agonist
Comment
Progestin, pregradiene derivative
Prevention of pregnancy in women who elect to use a hormonal contraceptive as a method of contraception
Target
NR3C3 (PGR) [HSA:5241] [KO:K08556]
  Pathway
hsa04114  Oocyte meiosis
hsa04914  Progesterone-mediated oocyte maturation
hsa04915  Estrogen signaling pathway
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03D PROGESTOGENS
    G03DB Pregnadien derivatives
     G03DB04 Nomegestrol
      D08281  Nomegestrol acetate (USAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C3 (PGR)
     D08281  Nomegestrol acetate (USAN)
BRITE hierarchy
Other DBs
CAS: 58652-20-3
PubChem: 96024968
ChEMBL: CHEMBL1476022
LigandBox: D08281
NIKKAJI: J296.996C
LinkDB All DBs
KCF data Show

ATOM        27
            1   C1z C    26.4600  -16.5900
            2   C1y C    26.4600  -17.9200
            3   C1x C    28.8400  -17.9200
            4   C1x C    28.8400  -16.5900
            5   C1z C    27.6500  -15.8900
            6   C1x C    25.2700  -15.8900
            7   C1x C    24.0800  -16.5900
            8   C1y C    24.0800  -17.9200
            9   C1y C    25.2700  -18.6200
            10  C1y C    22.9600  -18.6200
            11  C2y C    22.9600  -20.0200
            12  C2y C    24.0800  -20.6500
            13  C2x C    25.2700  -20.0200
            14  C1x C    21.8400  -17.9200
            15  C1x C    20.6500  -18.6200
            16  C5x C    20.6500  -20.0200
            17  C2x C    21.8400  -20.6500
            18  C1a C    26.4600  -15.1900
            19  C5a C    27.6500  -14.4900
            20  C1a C    26.4600  -13.7900
            21  O7a O    28.8400  -15.1900
            22  C1a C    24.0800  -22.0500
            23  O5x O    19.4600  -20.7200
            24  O5a O    28.8400  -13.7900
            25  C7a C    30.0581  -15.8801
            26  C1a C    31.2395  -15.1850
            27  O6a O    30.0698  -17.2894
BOND        30
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     1   6 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    9   2 1
            11    8  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 2
            15    9  13 1
            16   10  14 1
            17   14  15 1
            18   15  16 1
            19   16  17 1
            20   17  11 2
            21    1  18 1 #Up
            22    5  19 1 #Up
            23   19  20 1
            24    5  21 1 #Down
            25   12  22 1
            26   16  23 2
            27   19  24 2
            28   21  25 1
            29   25  26 1
            30   25  27 2

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