KEGG   DRUG: Norfenefrine
Entry
D08286                      Drug                                   

Name
Norfenefrine (INN)
Formula
C8H11NO2
Exact mass
153.079
Mol weight
153.1784
Structure
Simcomp
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01702  Phenethylamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
Remark
ATC code: C01CA05
Chemical structure group: DG00214
Efficacy
Cardiotonic
Comment
Phenethylamine derivative
Target
ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA05 Norfenefrine
      D08286  Norfenefrine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA1
     D08286  Norfenefrine (INN)
Other DBs
CAS: 536-21-0
PubChem: 96024973
ChEMBL: CHEMBL358040
LigandBox: D08286
NIKKAJI: J6.350I
LinkDB
KCF data

ATOM        11
            1   C8y C    13.5100  -27.2300
            2   C8x C    13.5100  -28.6300
            3   C8x C    14.7224  -29.3300
            4   C8x C    15.9349  -28.6300
            5   C8y C    15.9349  -27.2300
            6   C8x C    14.7224  -26.5300
            7   C1c C    17.1660  -26.5190
            8   C1b C    18.3712  -27.2147
            9   O1a O    17.1657  -25.1301
            10  N1a N    19.5535  -26.5319
            11  O1a O    12.2976  -26.5300
BOND        11
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     7   9 1
            10    8  10 1
            11    1  11 1

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