| Entry |
|
|---|
| Name |
Phenformin hydrochloride;
Debei (TN) |
|---|
| Formula |
C10H15N5. HCl
|
|---|
| Exact mass |
241.1094
|
|---|
| Mol weight |
241.72
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antidiabetic agent
DG01685 Insulin sensitizer
DG01684 Biguanide antidiabetic
DG02044 Hypoglycemic agent
DG01684 Biguanide antidiabetic
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Hypoglycemic |
|---|
| Comment |
Biguanide
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04920 | Adipocytokine signaling pathway |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BA Biguanides
A10BA01 Phenformin
D08352 Phenformin hydrochloride
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01684 Biguanide antidiabetic
DG00112 Phenformin
D08352 Phenformin hydrochloride
DG02044 Hypoglycemic agent
DG01684 Biguanide antidiabetic
DG00112 Phenformin
D08352 Phenformin hydrochloride
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00112 Phenformin
D08352 Phenformin hydrochloride
Target-based classification of drugs [BR:br08310]
Protein kinases
Serine/threonine kinases
CAMK group
AMPK (PRKAA)
D08352 Phenformin hydrochloride
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08352
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01684 Biguanide antidiabetic
DG00112 Phenformin
DG02044 Hypoglycemic agent
DG01684 Biguanide antidiabetic
DG00112 Phenformin
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00112 Phenformin
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 16
1 C8y C 19.8800 -15.4700
2 C1b C 18.6900 -14.7700
3 C8x C 19.8800 -16.8700
4 C8x C 21.0700 -14.7700
5 C1b C 17.4300 -15.4700
6 C8x C 21.0700 -17.5700
7 C8x C 22.3300 -15.4700
8 N1b N 16.2400 -14.7700
9 C8x C 22.3300 -16.8700
10 C2c C 15.0500 -15.4700
11 N1b N 13.7900 -14.7700
12 N2a N 15.0500 -16.8700
13 C2c C 12.6000 -15.4700
14 N1a N 11.4800 -14.7700
15 N2a N 12.6000 -16.8700
16 X Cl 24.3600 -16.0300
BOND 15
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 6 9 2
9 8 10 1
10 10 11 1
11 10 12 2
12 11 13 1
13 13 14 1
14 13 15 2
15 7 9 1
|
|---|
