KEGG   DRUG: PrasteroneHelp
Entry
D08409                      Drug                                   

Name
Prasterone (USAN/INN);
Biolaif (TN)
Product
Formula
C19H28O2
Exact mass
288.2089
Mol weight
288.4244
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01590  Androgen receptor agonist
  DG01605  Anabolic steroid
Remark
Same as: C01227
ATC code: A14AA07
Chemical structure group: DG00141
Product (DG00141): D08409<US> D01616<JP>
Efficacy
Accelerator (cervical ripening), Androgen receptor agonist
Comment
Androstan derivative
Target
NR3C4 (AR) [HSA:367] [KO:K08557]
NR3A (ESR) [HSA:2099 2100] [KO:K08550 K08551]
  Pathway
hsa04915  Estrogen signaling pathway
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A14 ANABOLIC AGENTS FOR SYSTEMIC USE
   A14A ANABOLIC STEROIDS
    A14AA Androstan derivatives
     A14AA07 Prasterone
      D08409  Prasterone (USAN/INN) <US>
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   Estrogen receptor
    NR3A (ESR)
     D08409  Prasterone (USAN/INN) <US>
   3-Ketosteroid receptor
    NR3C4 (AR)
     D08409  Prasterone (USAN/INN) <US>
BRITE hierarchy
Other DBs
CAS: 53-43-0
PubChem: 96025095
ChEBI: 28689
ChEMBL: CHEMBL309821 CHEMBL363554 CHEMBL90593
PDB-CCD: AND[PDBj]
LigandBox: D08409
NIKKAJI: J4.147E
LinkDB All DBs
KCF data Show

ATOM        21
            1   C1y C    25.3400  -18.9700
            2   C1y C    24.1500  -18.3400
            3   C1y C    26.4600  -18.2700
            4   C1x C    25.3400  -20.3700
            5   C1z C    22.9600  -18.9700
            6   C1x C    24.1500  -16.9400
            7   C1z C    26.5300  -16.9400
            8   C1x C    28.8400  -18.2700
            9   C2x C    24.1500  -21.0000
            10  C2y C    22.9600  -20.3000
            11  C1x C    21.8400  -18.3400
            12  C1a C    23.0300  -17.5000
            13  C1x C    25.3400  -16.2400
            14  C5x C    27.6500  -16.2400
            15  C1a C    26.5300  -15.2600
            16  C1x C    28.8400  -16.9400
            17  C1x C    21.8400  -21.0000
            18  C1x C    20.6500  -18.9700
            19  O5x O    27.6500  -14.9100
            20  C1y C    20.6500  -20.3000
            21  O1a O    19.5300  -21.0000
BOND        24
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 1
            11    5  12 1 #Up
            12    6  13 1
            13    7  14 1
            14    7  15 1 #Up
            15    8  16 1
            16   10  17 1
            17   11  18 1
            18   14  19 2
            19   17  20 1
            20   20  21 1 #Up
            21    7  13 1
            22    9  10 2
            23   14  16 1
            24   18  20 1

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