| Entry |
|
|---|
| Name |
Tetryzoline (INN);
Tetrahydrozoline;
Caltheon (TN) |
|---|
| Formula |
C13H16N2
|
|---|
| Exact mass |
200.1313
|
|---|
| Mol weight |
200.28
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Vasoconstrictor, alpha1-Adrenergic receptor agonist |
|---|
| Comment |
Imidazoline derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA06 Tetryzoline
D08578 Tetryzoline (INN)
R01AB Sympathomimetics, combinations excl. corticosteroids
R01AB03 Tetryzoline
D08578 Tetryzoline (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA02 Tetryzoline
D08578 Tetryzoline (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Tetryzoline
D08578 Tetryzoline (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG01030 Tetryzoline
D08578 Tetryzoline
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D08578 Tetryzoline (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG01030 Tetryzoline
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 15
1 C8x C 16.2400 -18.6900
2 C8x C 16.2400 -17.2900
3 C8x C 17.5000 -16.5900
4 C8y C 18.6900 -17.2900
5 C8y C 18.6900 -18.6900
6 C8x C 17.5000 -19.3900
7 C1y C 19.8800 -16.5900
8 C1x C 21.0700 -17.2900
9 C1x C 21.0700 -18.6900
10 C1x C 19.8800 -19.3900
11 C2y C 19.8800 -15.1200
12 N2x N 18.7600 -14.2800
13 C1x C 19.1800 -12.9500
14 C1x C 20.5800 -12.9500
15 N1x N 21.0000 -14.2800
BOND 17
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 7 11 1
13 11 12 2
14 12 13 1
15 13 14 1
16 14 15 1
17 11 15 1
|
|---|
