KEGG   DRUG: TranylcypromineHelp
Entry
D08625                      Drug                                   

Name
Tranylcypromine (INN);
Parnate (TN)
Formula
C9H11N
Exact mass
133.0891
Mol weight
133.1903
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01568  MAO inhibitor
  DG01519  Non-selective monoamine oxidase inhibitor
Remark
Same as: C07155
ATC code: N06AF04
Chemical structure group: DG00949
Product (DG00949): D00826<US>
Efficacy
Antidepressant, Monoamine oxidase (MAO) inhibitor
Target
MAO [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Structure map
map07027  Antidepressants
map07216  Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AF Monoamine oxidase inhibitors, non-selective
     N06AF04 Tranylcypromine
      D08625  Tranylcypromine (INN)
USP drug classification [BR:br08302]
 Antidepressants
  Monoamine Oxidase Inhibitors
   Tranylcypromine
    D08625  Tranylcypromine (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Amine oxidases
    MAO
     D08625  Tranylcypromine (INN)
BRITE hierarchy
Other DBs
CAS: 155-09-9
PubChem: 96025309
ChEBI: 9652
ChEMBL: CHEMBL467794
DrugBank: DB00752
LigandBox: D08625
NIKKAJI: J252.803G
LinkDB All DBs
KCF data Show

ATOM        10
            1   C1y C    24.7100  -17.1500
            2   C8y C    23.5200  -17.8500
            3   C1y C    26.1100  -17.1500
            4   C1x C    25.4100  -15.8900
            5   C8x C    22.2600  -17.1500
            6   C8x C    23.5200  -19.2500
            7   N1a N    27.3000  -17.8500
            8   C8x C    21.0700  -17.8500
            9   C8x C    22.2600  -19.9500
            10  C8x C    21.0700  -19.2500
BOND        11
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1 #Up
            7     5   8 1
            8     6   9 2
            9     8  10 2
            10    3   4 1
            11    9  10 1

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