KEGG   DRUG: Freeze-dried human blood-coagulation factor IX
Entry
D08797                      Drug                                   
Name
Freeze-dried human blood-coagulation factor IX;
Coagulation factor IX (recombinant);
Novact M (TN);
Rebinyn (TN);
Rixubis (TN)
Product
IXINITY (Medexus Pharma), REBINYN (Novo Nordisk)
Class
Blood modifier agent
 DG02016  Hemostatics
  DG02014  Blood coagulation accelerant
   DG02013  Blood coagulation factor
Remark
Therapeutic category: 6343
ATC code: B02BD04
Chemical structure group: DG00171
Product (DG00171): D08797<JP/US> D08794<JP> D05201<JP> D10757<JP> D10770<JP>
Efficacy
Bleeding suppressant, Replenisher (coagulation factor)
  Disease
Hemophilia B [DS:H00219]
Comment
See coagulation factor IXa [HSA:2158] [KO:K01321]
Target
F9* [HSA_VAR:2158v1] [HSA:2158] [KO:K01321]
  Pathway
hsa04610  Complement and coagulation cascades
  Network
nt06514  Coagulation cascade
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD04 Coagulation factor IX
      D08797  Freeze-dried human blood-coagulation factor IX <JP/US>
USP drug classification [BR:br08302]
 Blood Products and Modifiers
  Blood Component Deficiency/ Replacement
   Blood Component Deficiency/ Replacement, Hemophilia B
    Coagulation Factor IX (Recombinant)
     D08797  Freeze-dried human blood-coagulation factor IX
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   634  Human blood preparations
    6343  Plasma preparations
     D08797  Freeze-dried human blood-coagulation factor IX
Drug groups [BR:br08330]
 Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG02013  Blood coagulation factor
     DG00171  Blood coagulation factor IX
      D08797  Freeze-dried human blood-coagulation factor IX
Target-based classification of drugs [BR:br08310]
 Peptidases and inhibitors
  Serine peptidases
   Chymotrypsin family
    F9* [HSA_VAR:2158v1]
     D08797  Freeze-dried human blood-coagulation factor IX <JP/US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D08797
Drug groups [BR:br08330]
 Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG02013  Blood coagulation factor
     DG00171  Blood coagulation factor IX
Other DBs
PubChem: 96025480
LinkDB

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