| Entry |
|
|---|
| Name |
Tarenflurbil (USAN/INN);
R-Flurbiprofen |
|---|
| Formula |
C15H13FO2
|
|---|
| Exact mass |
244.0900
|
|---|
| Mol weight |
244.26
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Efficacy |
Dementia therapeutic agent, gamma-Secretase inhibitor |
|---|
| Comment |
Treatment of Alzheimer's disease
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Structure map |
| map07056 | Agents for Alzheimer-type dementia |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Aspartic peptidases
PSEN1/PSENEN/NCSTN/APH1A
D09010 Tarenflurbil (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 18
1 C8x C 16.1000 -15.8900
2 C8x C 16.1000 -17.2900
3 C8x C 17.3124 -17.9900
4 C8x C 18.5249 -17.2900
5 C8y C 18.5249 -15.8900
6 C8x C 17.3124 -15.1900
7 C8y C 19.7560 -15.1790
8 C8y C 20.9612 -15.8747
9 C8x C 22.1735 -15.1746
10 C8y C 22.1735 -13.7746
11 C8x C 20.9683 -13.0789
12 C8x C 19.7559 -13.7790
13 C1c C 23.3914 -13.0712
14 C6a C 24.6034 -13.7707
15 O6a O 25.7823 -13.0898
16 O6a O 24.6040 -15.1896
17 C1a C 23.3911 -11.6900
18 X F 20.9616 -17.2896
BOND 19
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 7 12 1
14 10 13 1
15 13 14 1
16 14 15 1
17 14 16 2
18 13 17 1 #Up
19 8 18 1
|
|---|
