| Entry |
|
|---|
| Name |
Zonampanel (INN/USAN) |
|---|
| Formula |
C13H9N5O6
|
|---|
| Exact mass |
331.0553
|
|---|
| Mol weight |
331.24
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG01569 AMPA receptor antagonist
|
|---|
| Efficacy |
Neuroprotectant, Stroke treatment, AMPA receptor antagonist |
|---|
| Comment |
Treatment of ischemic stroke
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG01569 AMPA receptor antagonist
D09035 Zonampanel
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), non-NMDA
GRIA
D09035 Zonampanel (INN/USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C8y C 17.3600 -15.1900
2 C8y C 17.3600 -16.5900
3 C8x C 18.5724 -17.2900
4 C8y C 19.7849 -16.5900
5 C8y C 19.7849 -15.1900
6 C8x C 18.5724 -14.4900
7 N4x N 20.9973 -17.2900
8 C8y C 22.2097 -16.5900
9 C8y C 22.2097 -15.1900
10 N4y N 20.9973 -14.4900
11 N4y N 16.1476 -14.4900
12 C8x C 16.0015 -13.1002
13 C8x C 14.6346 -12.8096
14 N5x N 13.9358 -14.0198
15 C8x C 14.8709 -15.0584
16 N2b N 16.1476 -17.2900 #+
17 O3a O 14.9521 -16.5996
18 O3a O 16.1475 -18.6898 #-
19 O5x O 23.4073 -14.4985
20 O5x O 23.4073 -17.2815
21 C1b C 20.9973 -13.0900
22 C6a C 22.2118 -12.3888
23 O6a O 23.4083 -13.0798
24 O6a O 22.2118 -10.9902
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 1 11 1
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 11 15 1
18 2 16 1
19 16 17 2
20 16 18 1
21 9 19 2
22 8 20 2
23 10 21 1
24 21 22 1
25 22 23 1
26 22 24 2
|
|---|
