| Entry |
|
|---|
| Name |
Dutogliptin (USAN) |
|---|
| Formula |
C10H20BN3O3
|
|---|
| Exact mass |
241.1598
|
|---|
| Mol weight |
241.10
|
|---|
| Structure |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) inhibitor |
|---|
| Comment |
Treatment of type 2 diabetes
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04974 | Protein digestion and absorption |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01601 DPP-4 inhibitor
DG01282 Dutogliptin
D09333 Dutogliptin
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Serine peptidases
Prolyl oligopeptidase family
DPP4 (CD26)
D09333 Dutogliptin (USAN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01601 DPP-4 inhibitor
DG01282 Dutogliptin
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 17
1 N1x N 8.8200 -25.4800
2 C1x C 9.2400 -26.7400
3 C1x C 10.6400 -26.7400
4 C1y C 11.0600 -25.4100
5 C1x C 9.9400 -24.5700
6 N1b N 12.2500 -24.7100
7 C1b C 13.4400 -25.4100
8 C5a C 14.6300 -24.7100
9 N1y N 15.8200 -25.4100
10 O5a O 14.6300 -23.3100
11 C1x C 16.1700 -26.8100
12 C1x C 17.5700 -26.8100
13 C1x C 18.0600 -25.5500
14 C1y C 17.0100 -24.6400
15 Z B 17.0378 -23.2434
16 O1a O 18.2438 -22.5784
17 O1a O 15.8177 -22.5062
BOND 18
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 6 7 1
7 4 6 1 #Down
8 7 8 1
9 8 9 1
10 8 10 2
11 9 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 9 14 1
16 14 15 1 #Down
17 15 16 1
18 15 17 1
|
|---|
