| Entry |
|
|---|
| Name |
Naluzotan hydrochloride (USAN) |
|---|
| Formula |
C23H38N4O3S. HCl
|
|---|
| Exact mass |
486.2431
|
|---|
| Mol weight |
487.10
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antianxiety, Antidepressant, Serotonin 5-HT1A receptor agonist |
|---|
| Comment |
Treatment of depression and anxiety disorder
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG01279 Naluzotan
D09359 Naluzotan hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR1A
D09359 Naluzotan hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG01279 Naluzotan
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C8x C 18.8300 -21.0700
2 C8y C 18.8300 -22.4700
3 C8x C 17.6400 -23.1700
4 C8y C 16.3800 -22.4700
5 C8x C 16.3800 -21.0700
6 C8x C 17.6400 -20.3700
7 N1b N 15.1900 -23.1700
8 C5a C 14.0000 -22.4700
9 C1a C 12.8100 -23.1700
10 O5a O 14.0000 -21.0700
11 N1y N 20.0200 -23.1700
12 C1x C 21.2100 -22.4700
13 C1x C 22.4700 -23.1700
14 N1y N 22.4700 -24.5700
15 C1x C 21.2800 -25.2700
16 C1x C 20.0200 -24.5700
17 C1b C 23.6600 -25.2700
18 C1b C 24.8500 -24.5700
19 C1b C 26.0400 -25.2700
20 C1b C 27.2300 -24.5700
21 N1b N 28.3500 -25.2700
22 S4a S 29.5400 -24.5700
23 C1b C 30.7300 -25.2700
24 C1y C 31.9200 -24.5700
25 C1x C 31.9200 -23.1700
26 C1x C 33.1800 -22.4700
27 C1x C 34.3700 -23.1700
28 C1x C 34.3700 -24.5700
29 C1x C 33.1800 -25.2700
30 O3c O 30.5900 -23.5900
31 O3c O 28.4200 -23.5200
32 X Cl 30.8000 -20.5100
BOND 33
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 8 10 2
11 2 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 11 16 1
18 14 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 25 26 1
28 26 27 1
29 27 28 1
30 28 29 1
31 24 29 1
32 22 30 2
33 22 31 2
|
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