KEGG T01001: 3350

Homo sapiens (human): 3350

Entry

3350              CDS       T01001

Symbol

HTR1A, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD

Name

(RefSeq) 5-hydroxytryptamine receptor 1A

K04153

5-hydroxytryptamine receptor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04024

cAMP signaling pathway

hsa04080

Neuroactive ligand-receptor interaction

hsa04726

Serotonergic synapse

hsa04742

Taste transduction

Disease

H02773

Menstrual cycle-dependent periodic fever

Drug target

Adatanserin hydrochloride:

D02767

Aripiprazole (DG00906):

D01164<JP/US> D10355 D10364<US> D10516<JP/US>

Asenapine (DG03100):

D02995<JP/US>

Bifeprunox (DG01304):

D06566 D06567

Binospirone mesylate:

D03121

Brexpiprazole:

D10309<JP/US>

Buspirone (DG00913):

D00702<US> D07593

Cariprazine (DG01305):

D09876<US> D09997

Cinitapride (DG01520):

D07700 D07701

Cyproheptadine (DG01109):

D02234<JP/US> D07765

Eptapirone:

D02576

Ergot alkaloids:

D07906

Ergotamine (DG00834):

D00679<US>

Flesinoxan:

D02568

Flibanserin:

D02577<US>

Gepirone:

D04314<US>

Indorenate hydrochloride:

D04533

Ipsapirone hydrochloride:

D04611

Lecozotan hydrochloride:

D04683

Methysergide (DG00835):

D00681 D02357

Naluzotan (DG01279):

D09358 D09359

Pardoprunox (DG01324):

D09366 D09397

Pipotiazine (DG00884):

D02680 D08385

Pizotifen (DG00842):

D05523 D08397

Sarizotan hydrochloride:

D05804

Sunepitron hydrochloride:

D02569

Tandospirone (DG01306):

D01992<JP> D08561

Tiospirone hydrochloride:

D02688

Ulotaront (DG03247):

D12474 D12475

Vilazodone (DG00964):

D09698 D09699<US>

Vortioxetine (DG00965):

D10184 D10185<JP/US> D12544

Xaliproden (DG01008):

D01537 D06327

Zalospirone hydrochloride:

D06354

Zotepine:

D01321<JP>

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3350 (HTR1A)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3350 (HTR1A)
09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3350 (HTR1A)
  09157 Sensory system
   04742 Taste transduction
    3350 (HTR1A)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    3350 (HTR1A)
G protein-coupled receptors [BR:hsa04030]
Rhodopsin family
  Biogenic amine
   Serotonin
    3350 (HTR1A)

SSDB

Motif

Pfam:

7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

5:complement(63957874..63962445)

AA seq 422 aa
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ

NT seq 1269 nt +upstreamnt +downstreamnt
atggatgtgctcagccctggtcagggcaacaacaccacatcaccaccggctccctttgag
accggcggcaacactactggtatctccgacgtgaccgtcagctaccaagtgatcacctct
ctgctgctgggcacgctcatcttctgcgcggtgctgggcaatgcgtgcgtggtggctgcc
atcgccttggagcgctccctgcagaacgtggccaattatcttattggctctttggcggtc
accgacctcatggtgtcggtgttggtgctgcccatggccgcgctgtatcaggtgctcaac
aagtggacactgggccaggtaacctgcgacctgttcatcgccctcgacgtgctgtgctgc
acctcatccatcttgcacctgtgcgccatcgcgctggacaggtactgggccatcacggac
cccatcgactacgtgaacaagaggacgccccggcgcgccgctgcgctcatctcgctcact
tggcttattggcttcctcatctctatcccgcccatgctgggctggcgcaccccggaagac
cgctcggaccccgacgcatgcaccattagcaaggatcatggctacactatctattccacc
tttggagctttctacatcccgctgctgctcatgctggttctctatgggcgcatattccga
gctgcgcgcttccgcatccgcaagacggtcaaaaaggtggagaagaccggagcggacacc
cgccatggagcatctcccgccccgcagcccaagaagagtgtgaatggagagtcggggagc
aggaactggaggctgggcgtggagagcaaggctgggggtgctctgtgcgccaatggcgcg
gtgaggcaaggtgacgatggcgccgccctggaggtgatcgaggtgcaccgagtgggcaac
tccaaagagcacttgcctctgcccagcgaggctggtcctaccccttgtgcccccgcctct
ttcgagaggaaaaatgagcgcaacgccgaggcgaagcgcaagatggccctggcccgagag
aggaagacagtgaagacgctgggcatcatcatgggcaccttcatcctctgctggctgccc
ttcttcatcgtggctcttgttctgcccttctgcgagagcagctgccacatgcccaccctg
ttgggcgccataatcaattggctgggctactccaactctctgcttaaccccgtcatttac
gcatacttcaacaaggactttcaaaacgcgtttaagaagatcattaagtgtaagttctgc
cgccagtga

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