KEGG   DRUG: FavipiravirHelp
Entry
D09537                      Drug                                   

Name
Favipiravir (JAN/USAN/INN);
Avigan (TN)
Formula
C5H4FN3O2
Exact mass
157.0288
Mol weight
157.1026
Structure
Mol fileKCF fileDB search
Class
Metabolizing enzyme substrate
 DG02953  AOX substrate
Metabolizing enzyme inhibitor
 DG01641  CYP2C8 inhibitor
 DG02952  AOX inhibitor
Remark
Therapeutic category: 6250
Product: D09537<JP>
Efficacy
Antiviral, RNA replicase inhibitor
Target
RNA-directed RNA polymerase
Metabolism
Enzyme: AOX1 [HSA:316]; XDH [HSA:7498]
Interaction
CYP inhibition: CYP2C8 [HSA:1558]
Enzyme inhibition: AOX1 [HSA:316]
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D09537  Favipiravir (JAN/USAN/INN)
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09537
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09537
BRITE hierarchy
Other DBs
CAS: 259793-96-9
PubChem: 96026217
ChEMBL: CHEMBL221722
LigandBox: D09537
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8x C    17.8500  -21.4200
            2   C8y C    17.8500  -20.0200
            3   N5x N    19.0400  -19.3200
            4   C8y C    20.3000  -20.0200
            5   C8y C    20.3000  -21.4200
            6   N5x N    19.0400  -22.1200
            7   X   F    16.6600  -19.3200
            8   O1a O    21.4900  -22.1200
            9   C5a C    21.4900  -19.3200
            10  N1a N    22.6800  -20.0200
            11  O5a O    21.4900  -17.9200
BOND        11
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     5   8 1
            9     4   9 1
            10    9  10 1
            11    9  11 2

» Japanese version   » Back

DBGET integrated database retrieval system