| Entry |
|
|---|
| Name |
Gosogliptin (USAN/INN) |
|---|
| Formula |
C17H24F2N6O
|
|---|
| Exact mass |
366.1980
|
|---|
| Mol weight |
366.41
|
|---|
| Structure |
|
|---|
| Class |
|
|---|
| Efficacy |
Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) inhibitor |
|---|
| Comment |
Treatment of diabetes
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04974 | Protein digestion and absorption |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01601 DPP-4 inhibitor
D09625 Gosogliptin
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-peptidases
DPP4 (CD26)
D09625 Gosogliptin (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C8x C 9.7300 -25.8300
2 C8x C 9.7300 -27.2300
3 C8x C 10.9200 -27.9300
4 N5x N 12.1800 -27.2300
5 C8y C 12.1800 -25.8300
6 N5x N 10.9200 -25.1300
7 N1y N 13.3700 -25.1300
8 C1x C 14.5600 -25.8300
9 C1x C 15.8200 -25.1300
10 N1y N 15.8200 -23.7300
11 C1x C 14.6300 -23.0300
12 C1x C 13.3700 -23.7300
13 C1y C 17.0100 -23.0300
14 N1x N 18.8300 -21.7000
15 C1x C 17.4300 -21.7000
16 C1x C 18.1300 -23.8700
17 C1y C 19.2500 -23.0300
18 C5a C 20.4400 -23.7300
19 N1y N 21.6300 -23.0300
20 O5a O 20.4400 -25.1300
21 C1x C 23.4500 -21.7000
22 C1x C 22.0500 -21.7000
23 C1x C 22.7500 -23.8700
24 C1z C 23.8700 -23.0300
25 X F 24.5700 -24.2900
26 X F 25.2700 -23.0300
BOND 29
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 7 12 1
14 13 10 1 #Down
15 14 15 1
16 15 13 1
17 13 16 1
18 16 17 1
19 14 17 1
20 17 18 1 #Down
21 18 19 1
22 18 20 2
23 21 22 1
24 22 19 1
25 19 23 1
26 23 24 1
27 21 24 1
28 24 25 1
29 24 26 1
|
|---|
