| Entry |
|
|---|
| Name |
Narlaprevir (USAN/INN) |
|---|
| Formula |
C36H61N5O7S
|
|---|
| Exact mass |
707.4292
|
|---|
| Mol weight |
707.97
|
|---|
| Structure |
|
|---|
| Class |
Antiviral
DG03198 Anti-HCV agent
DG02001 HCV NS3/4A protease inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiviral, Protease inhibitor |
|---|
| Comment |
Treatment of hepatitis C
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AP Antivirals for treatment of HCV infections
J05AP14 Narlaprevir
D09644 Narlaprevir (USAN/INN)
Drug groups [BR:br08330]
Antiviral
DG03198 Anti-HCV agent
DG02001 HCV NS3/4A protease inhibitor
D09644 Narlaprevir
Antimicrobials [BR:br08307]
Antivirals
Polyprotein cleavage inhibitor
HCV NS3/4A inhibitor
D09644 Narlaprevir (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 49
1 C1y C 16.5200 -25.2700
2 C1x C 16.1000 -26.6000
3 N1y N 17.2200 -27.4400
4 C1y C 18.3400 -26.6000
5 C1y C 17.9200 -25.2700
6 C1z C 17.2200 -24.0800
7 C1a C 16.5200 -22.8900
8 C1a C 17.9200 -22.8900
9 C5a C 19.5300 -27.3000
10 N1b N 20.7200 -26.6000
11 O5a O 19.5300 -28.7000
12 C1c C 21.9100 -27.3000
13 C5a C 23.1000 -26.6000
14 C1b C 21.9100 -28.7000
15 C1b C 23.1000 -29.4000
16 C5a C 24.2900 -27.3000
17 O5a O 23.1000 -25.2000
18 N1b N 25.4800 -26.6000
19 O5a O 24.2900 -28.7000
20 C1y C 26.6700 -27.3000
21 C1x C 27.3700 -28.5600
22 C1x C 28.0700 -27.3000
23 C1b C 23.1000 -30.8000
24 C1a C 24.2900 -31.5000
25 C5a C 17.2200 -28.8400
26 C1c C 16.0300 -29.5400
27 O5a O 18.4100 -29.5400
28 N1b N 14.8400 -28.8400
29 C1d C 16.0300 -30.9400
30 C1a C 14.8400 -31.6400
31 C1a C 17.2200 -31.6400
32 C1a C 16.0300 -32.3400
33 C5a C 13.6500 -29.5400
34 N1b N 12.4600 -28.8400
35 O5a O 13.6500 -30.9400
36 C1z C 11.2700 -29.5400
37 C1b C 10.0800 -28.8400
38 C1x C 10.0800 -30.2400
39 C1x C 10.0800 -31.6400
40 C1x C 11.2700 -32.3400
41 C1x C 12.5300 -31.6400
42 C1x C 12.5300 -30.2400
43 S4a S 8.8619 -29.5301
44 C1d C 7.6805 -28.8350
45 C1a C 6.4751 -29.5180
46 O3c O 8.8619 -28.1301
47 O3c O 8.8619 -30.9301
48 C1a C 7.6919 -27.4400
49 C1a C 6.4905 -28.1349
BOND 52
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 5 6 1
7 6 1 1
8 6 7 1
9 6 8 1
10 4 9 1 #Up
11 9 10 1
12 9 11 2
13 10 12 1
14 12 13 1
15 12 14 1 #Down
16 14 15 1
17 13 16 1
18 13 17 2
19 16 18 1
20 16 19 2
21 18 20 1
22 20 21 1
23 21 22 1
24 22 20 1
25 15 23 1
26 23 24 1
27 3 25 1
28 25 26 1
29 25 27 2
30 26 28 1
31 26 29 1 #Down
32 29 30 1
33 29 31 1
34 29 32 1
35 28 33 1
36 33 34 1
37 33 35 2
38 34 36 1
39 36 37 1
40 38 39 1
41 39 40 1
42 40 41 1
43 41 42 1
44 42 36 1
45 38 36 1
46 37 43 1
47 43 44 1
48 44 45 1
49 43 46 2
50 43 47 2
51 44 48 1
52 44 49 1
|
|---|
