KEGG   DRUG: VerucerfontHelp
Entry
D09695                      Drug                                   

Name
Verucerfont (USAN/INN)
Formula
C22H26N6O2
Exact mass
406.2117
Mol weight
406.4808
Structure
Mol fileKCF fileDB search
Efficacy
Antianxiety, Antidepressant, Corticotropin releasing hormone receptor 1 antagonist
Comment
Treatment of depression and anxiety
Target
CRHR1 [HSA:1394] [KO:K04578]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Corticotropin-releasing hormone
    CRHR1
     D09695  Verucerfont (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 885220-61-1
PubChem: 124490435
ChEMBL: CHEMBL1287935
LigandBox: D09695
LinkDB All DBs
KCF data Show

ATOM        30
            1   C8y C    16.5218  -15.5620
            2   C8x C    16.5218  -16.9664
            3   C8y C    17.7380  -17.6686
            4   N5x N    18.9544  -16.9664
            5   C8y C    18.9544  -15.5620
            6   N4y N    17.7380  -14.8598
            7   C8y C    19.9981  -14.6222
            8   C8y C    19.4269  -13.3391
            9   N5x N    18.0300  -13.4860
            10  C1a C    17.7380  -19.0729
            11  C1a C    20.1330  -12.1164
            12  C8y C    21.4105  -14.6410
            13  C8y C    22.1060  -15.8841
            14  C8x C    23.5104  -15.9031
            15  C8y C    24.2289  -14.6963
            16  C8x C    23.5334  -13.4533
            17  C8x C    22.1291  -13.4343
            18  C1a C    21.3836  -17.0967
            19  N1b N    15.3055  -14.8598
            20  C1c C    14.1062  -15.5523
            21  C1b C    12.9150  -14.8647
            22  C8y C    14.1061  -16.9661
            23  N5x N    12.9883  -17.7785
            24  C8y C    13.4155  -19.0925
            25  N5x N    14.7973  -19.0923
            26  O2x O    15.2241  -17.7782
            27  C1a C    12.6051  -20.2083
            28  C1a C    11.7201  -15.5549
            29  O2a O    25.6199  -14.7151
            30  C1a C    26.3429  -13.5011
BOND        33
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 2
            8     7   8 1
            9     8   9 2
            10    6   9 1
            11    3  10 1
            12    8  11 1
            13    7  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   12  17 1
            20   13  18 1
            21    1  19 1
            22   19  20 1
            23   20  21 1 #Down
            24   20  22 1
            25   22  23 2
            26   23  24 1
            27   24  25 2
            28   25  26 1
            29   22  26 1
            30   24  27 1
            31   21  28 1
            32   15  29 1
            33   29  30 1

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