KEGG   DRUG: Ipidacrine hydrochloride hydrate
Entry
D09750                      Drug                                   
Name
Ipidacrine hydrochloride hydrate (JAN)
Formula
C12H16N2. HCl. H2O
Exact mass
242.1186
Mol weight
242.7451
Structure
Class
Neuropsychiatric agent
 DG01595  Cholinesterase inhibitor
  DG01593  Acetylcholinesterase inhibitor
 DG01968  Antidementia agent
Remark
ATC code: N06DA05
Efficacy
Dementia therapeutic agent, Acetylcholinesterase inhibitor
Comment
Acridine derivative
Target
ACHE [HSA:43] [KO:K01049]
  Pathway
hsa00564  Glycerophospholipid metabolism
hsa04725  Cholinergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06D ANTI-DEMENTIA DRUGS
    N06DA Anticholinesterases
     N06DA05 Ipidacrine
      D09750  Ipidacrine hydrochloride hydrate (JAN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01595  Cholinesterase inhibitor
   DG01593  Acetylcholinesterase inhibitor
    D09750  Ipidacrine hydrochloride hydrate
  DG01968  Antidementia agent
   D09750  Ipidacrine hydrochloride hydrate
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Carboxylic-ester hydrolases
    ACHE
     D09750  Ipidacrine hydrochloride hydrate (JAN)
Other DBs
PubChem: 124490490
LigandBox: D09750
LinkDB
KCF data

ATOM        16
            1   C1x C    19.1100  -20.1600
            2   C1x C    19.1100  -21.5600
            3   C1x C    20.3224  -22.2600
            4   C8y C    21.5349  -21.5600
            5   C8y C    21.5349  -20.1600
            6   C1x C    20.3224  -19.4600
            7   N5x N    22.7473  -22.2600
            8   C8y C    23.9597  -21.5600
            9   C8y C    23.9597  -20.1600
            10  C8y C    22.7473  -19.4600
            11  C1x C    25.2912  -21.9926
            12  C1x C    26.1141  -20.8600
            13  C1x C    25.2912  -19.7274
            14  N1a N    22.7473  -18.0600
            15  X   Cl   28.2800  -19.6000
            16  O0  O    28.7000  -21.0700
BOND        16
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 2
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 2
            12    8  11 1
            13   11  12 1
            14   12  13 1
            15    9  13 1
            16   10  14 1

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