KEGG   DRUG: Isoniazid glucuronate sodium
Entry
D09773                      Drug                                   

Name
Isoniazid glucuronate sodium (JAN)
Formula
C12H14N3O7. 2H2O. Na
Exact mass
371.0941
Mol weight
371.2758
Structure
Class
Antibacterial
 DG01966  Antitubercular
Neuropsychiatric agent
 DG01568  MAO inhibitor
  DG01519  Non-selective monoamine oxidase inhibitor
Remark
ATC code: J04AC01
Chemical structure group: DG00642
Product (DG00642): D00346<JP/US> D02002<JP>
Efficacy
Antibacterial (tuberculostatic)
Target
enoyl-[acyl-carrier-protein] reductase (NADH) [KO:K11611]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AC Hydrazides
     J04AC01 Isoniazid
      D09773  Isoniazid glucuronate sodium (JAN)
Antimicrobials [BR:br08307]
 Antibacterials
  Other antibacterials
   Mycolic acid biosynthesis inhibitor
    D09773  Isoniazid glucuronate sodium (JAN)
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Other antibacterials
   Mycolic acid biosynthesis inhibitor
    DG00642  Isoniazid
Other DBs
PubChem: 124490513
LigandBox: D09773
LinkDB
KCF data

ATOM        25
            1   C8x C    22.1900  -18.2700
            2   C8y C    22.1900  -19.6700
            3   C8x C    21.0000  -20.3700
            4   C8x C    19.7400  -19.6700
            5   N5x N    19.7400  -18.2700
            6   C8x C    21.0000  -17.5700
            7   C5a C    23.3800  -20.3700
            8   N1b N    24.5700  -19.6700
            9   O5a O    23.3800  -21.7700
            10  N2b N    25.7600  -20.3700
            11  C2b C    26.9500  -19.6700
            12  C1c C    28.1400  -20.3700
            13  C1c C    29.3300  -19.6700
            14  C1c C    30.5200  -20.3700
            15  O1a O    28.1400  -21.7700
            16  O1a O    29.3300  -18.2700
            17  C1c C    31.7100  -19.6700
            18  O1a O    30.5200  -21.7700
            19  C6a C    32.9000  -20.3700
            20  O1a O    31.7100  -18.2700
            21  O6a O    34.0900  -19.6700 #-
            22  O6a O    32.9000  -21.7700
            23  Z   Na   36.5267  -18.2975 #+
            24  O0  O    38.2200  -21.2800
            25  O0  O    38.2200  -21.2800
BOND        22
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     7   9 2
            10    8  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   12  15 1 #Up
            16   13  16 1 #Up
            17   14  17 1
            18   14  18 1 #Up
            19   17  19 1
            20   17  20 1 #Down
            21   19  21 1
            22   19  22 2
BRACKET     1    36.1200  -22.2600   36.1200  -20.1600
            1    38.9200  -20.1600   38.9200  -22.2600
            1  2
 ORIGINAL  1   24
 REPEAT    1   25

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