| Entry |
|
|---|
| Name |
Ceftizoxime alapivoxil hydrochloride (JAN) |
|---|
| Formula |
C22H28N6O8S2. HCl
|
|---|
| Exact mass |
604.1177
|
|---|
| Mol weight |
605.09
|
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| Structure |
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| Simcomp |
|
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| Class |
|
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| Remark |
| Product (DG00576): | D00923<JP> |
|
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Ceftizoxime [DR: D07658]
|
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| Target |
penicillin binding protein |
|---|
| Pathway |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD07 Ceftizoxime
D09793 Ceftizoxime alapivoxil hydrochloride (JAN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00576 Ceftizoxime
D09793 Ceftizoxime alapivoxil hydrochloride
DG01776 Third-generation cephalosporin
DG00576 Ceftizoxime
D09793 Ceftizoxime alapivoxil hydrochloride
DG01804 Oxyimino beta-lactam
DG00576 Ceftizoxime
D09793 Ceftizoxime alapivoxil hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D09793 Ceftizoxime alapivoxil hydrochloride (JAN)
Prodrugs [br08324.html]
D09793
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00576 Ceftizoxime
DG01776 Third-generation cephalosporin
DG00576 Ceftizoxime
DG01804 Oxyimino beta-lactam
DG00576 Ceftizoxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00576 Ceftizoxime
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 39
1 X Cl 34.1600 -25.3400
2 C1y C 28.1400 -28.1400
3 N1y N 28.1400 -29.4700
4 C2y C 29.4000 -30.1700
5 C2x C 30.5900 -29.4700
6 C1x C 30.5900 -28.1400
7 S2x S 29.4000 -27.4400
8 C1y C 26.7400 -28.1400
9 C5x C 26.7400 -29.4700
10 N1b N 25.5500 -27.4400
11 C5a C 24.3600 -28.1400
12 O5a O 24.3600 -29.4700
13 O5x O 25.5500 -30.1700
14 C2c C 23.1700 -27.4400
15 C8y C 21.9100 -28.1400
16 C8x C 20.7900 -27.3000
17 S2x S 19.6700 -28.1400
18 C8y C 20.0900 -29.4700
19 N5x N 21.4900 -29.4700
20 N2b N 23.1700 -25.9700
21 C7a C 29.4000 -31.6400
22 O7a O 30.5900 -32.3400
23 O6a O 28.1400 -32.3400
24 O2a O 24.3600 -25.3400
25 C1a C 24.3600 -23.9400
26 C1b C 31.7800 -31.6400
27 O7a O 32.9700 -32.3400
28 C7a C 34.1600 -31.6400
29 C1d C 35.3500 -32.3400
30 O6a O 34.1600 -30.2400
31 C1a C 36.6100 -31.6400
32 C1a C 35.3500 -33.7400
33 C1a C 36.5400 -33.0400
34 C5a C 17.7100 -29.4700
35 N1b N 18.9000 -30.1700
36 C1c C 16.5200 -30.1700
37 O5a O 17.7100 -28.0700
38 C1a C 15.3300 -29.4700
39 N1a N 16.5200 -31.5700
BOND 40
1 2 3 1
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 1
6 2 7 1
7 2 8 1
8 8 9 1
9 3 9 1
10 8 10 1 #Up
11 10 11 1
12 11 12 2
13 9 13 2
14 11 14 1
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 1
19 18 19 2
20 15 19 1
21 14 20 2
22 4 21 1
23 21 22 1
24 21 23 2
25 20 24 1
26 24 25 1
27 22 26 1
28 26 27 1
29 27 28 1
30 28 29 1
31 28 30 2
32 29 31 1
33 29 32 1
34 29 33 1
35 34 35 1
36 35 18 1
37 34 36 1
38 34 37 2
39 36 38 1
40 36 39 1 #Up
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