KEGG   DRUG: Dalantercept
Entry
D10106                      Drug                                   
Name
Dalantercept (USAN)
Formula
H3206H4960N904O976S38
Exact mass
37714.6535
Mol weight
37726.7792
Sequence
DPVKPSRGPL VTCTCESPHC KGPTCRGAWC TVVLVREEGR HPQEERGCGN LHRELCRGRP
TEFVNHYCCD SHLCNHNVSL VLEATQPPSE QPGTDGQLAT GGGTHTCPPC PAPEALGAPS
VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST
YRVVSVLTVL HQDWLNGKEY KCKVSNKALP VPIEKTISKA KGQPREPQVY TLPPSREEMT
KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGPFFLYSK LTVDKSRWQQ
GNVFSCSVMH EALHNHYTQK SLSLSPGK
(Disulfide bridge: 13-30, 15-20, 25-48, 56-68, 69-74, 107-107', 110-110', 1442-202, 248-306, 13'-30', 15'-20', 25'-48', 56'-68', 69'-74', 142'-202', 248'-306')
  Type
Peptide
Efficacy
Antineoplastic, Angiogenesis inhibitor
Comment
ALK1-Fc fusion protein
Target
ACVRL1 [HSA:94] [KO:K13594]
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor serine/threonine kinases (RSTK)
   TGFBR1 family
    ACVRL1
     D10106  Dalantercept (USAN)
Other DBs
CAS: 1186210-24-1
PubChem: 135626824
LinkDB

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