KEGG   DRUG: Mericitabine
Entry
D10477                      Drug                                   
Name
Mericitabine (USAN/INN)
Formula
C18H26FN3O6
Exact mass
399.1806
Mol weight
399.41
Structure
Class
Antiviral
 DG01440  Arabinofuranosyl type antiviral
 DG03198  Anti-HCV agent
  DG02000  HCV NS5B polymerase inhibitor
Efficacy
Antiviral, NS5B polymerase inhibitor
Comment
Treatment of hepatitis C
Target
HCV NS5B polymerase [KO:K22472]
  Pathway
ko03230  Viral genome structure
ko03240  Viral replication
ko05160  Hepatitis C
Brite
Drug groups [BR:br08330]
 Antiviral
  DG01440  Arabinofuranosyl type antiviral
   D10477  Mericitabine
  DG03198  Anti-HCV agent
   DG02000  HCV NS5B polymerase inhibitor
    D10477  Mericitabine
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   HCV NS5A/NS5B inhibitor
    D10477  Mericitabine (USAN/INN)
Other DBs
CAS: 940908-79-2
PubChem: 172232570
LinkDB
KCF data

ATOM        28
            1   C1z C    22.3300  -16.7300
            2   C1y C    22.6800  -15.3300
            3   O2x O    21.5600  -14.5600
            4   C1y C    20.4400  -15.4000
            5   C1y C    20.9300  -16.7300
            6   N5x N    26.3200  -14.6300
            7   C8y C    26.3200  -13.2300
            8   C8x C    25.1300  -12.5300
            9   C8x C    23.8700  -13.2300
            10  N4y N    23.8700  -14.6300
            11  C8y C    25.1300  -15.3300
            12  O5x O    25.1300  -16.7300
            13  N1a N    27.5100  -12.5300
            14  C1b C    19.2500  -14.7000
            15  O7a O    18.0600  -15.4000
            16  C7a C    16.8700  -14.7000
            17  C1c C    15.6800  -15.4000
            18  O6a O    16.8700  -13.3000
            19  C1a C    14.4900  -14.7000
            20  C1a C    15.6800  -16.8000
            21  O7a O    19.7400  -17.4300
            22  C7a C    19.7400  -18.8300
            23  C1c C    18.5500  -19.5300
            24  O6a O    20.9300  -19.5300
            25  C1a C    17.3600  -18.8300
            26  C1a C    18.5500  -20.9300
            27  X   F    23.7300  -16.7300
            28  C1a C    22.3300  -18.1300
BOND        29
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     6   7 2
            7     7   8 1
            8     8   9 2
            9     9  10 1
            10   10  11 1
            11    6  11 1
            12    2  10 1 #Up
            13   11  12 2
            14    7  13 1
            15    4  14 1 #Up
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   16  18 2
            20   17  19 1
            21   17  20 1
            22    5  21 1 #Down
            23   21  22 1
            24   22  23 1
            25   22  24 2
            26   23  25 1
            27   23  26 1
            28    1  27 1 #Down
            29    1  28 1 #Up

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