| Entry |
|
|---|
| Name |
Gemigliptin (INN) |
|---|
| Formula |
C18H19F8N5O2
|
|---|
| Exact mass |
489.1411
|
|---|
| Mol weight |
489.36
|
|---|
| Structure |
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|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa04974 | Protein digestion and absorption |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors
A10BH06 Gemigliptin
D10502 Gemigliptin (INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01601 DPP-4 inhibitor
D10502 Gemigliptin
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-peptidases
DPP4 (CD26)
D10502 Gemigliptin (INN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 33
1 C1x C 7.1400 -16.3800
2 C1x C 7.1400 -17.7800
3 C5x C 8.3524 -18.4800
4 N1y N 9.5649 -17.7800
5 C1x C 9.5649 -16.3800
6 C1z C 8.3524 -15.6800
7 X F 9.0524 -14.4676
8 X F 7.6524 -14.4676
9 O5x O 8.3524 -19.8798
10 C1b C 10.7960 -18.4910
11 C1c C 12.0012 -17.7953
12 C1b C 13.1835 -18.4781
13 N1a N 12.0016 -16.3804
14 C5a C 14.3775 -17.7888
15 N1y N 15.5654 -18.4748
16 O5a O 14.3777 -16.3803
17 C1x C 15.5654 -19.8798
18 C1x C 16.7778 -20.5798
19 C8y C 17.9903 -19.8798
20 C8y C 17.9903 -18.4748
21 C1x C 16.7779 -17.7748
22 C8y C 19.2027 -20.5798
23 N5x N 20.4151 -19.8799
24 C8y C 20.4152 -18.4749
25 N5x N 19.2027 -17.7749
26 C1d C 21.6438 -17.7653
27 X F 22.8563 -17.0653
28 X F 22.3438 -18.9777
29 X F 20.9438 -16.5528
30 C1d C 19.2027 -21.9798
31 X F 20.6027 -21.9798
32 X F 17.8027 -21.9798
33 X F 19.2027 -23.3798
BOND 35
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 6 7 1
8 6 8 1
9 3 9 2
10 4 10 1
11 10 11 1
12 11 12 1
13 11 13 1 #Up
14 12 14 1
15 14 15 1
16 14 16 2
17 15 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 15 21 1
23 19 22 2
24 22 23 1
25 23 24 2
26 24 25 1
27 20 25 2
28 24 26 1
29 26 27 1
30 26 28 1
31 26 29 1
32 22 30 1
33 30 31 1
34 30 32 1
35 30 33 1
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