| Entry |
|
|---|
| Name |
Dasabuvir (USAN/INN) |
|---|
| Formula |
C26H27N3O5S
|
|---|
| Exact mass |
493.1671
|
|---|
| Mol weight |
493.58
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG03198 Anti-HCV agent
DG02000 HCV NS5B polymerase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiviral, NS5B polymerase inhibitor |
|---|
| Target |
HCV NS5B polymerase [KO: K22472] |
|---|
| Pathway |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AP Antivirals for treatment of HCV infections
J05AP09 Dasabuvir
D10553 Dasabuvir (USAN/INN)
Drug groups [BR:br08330]
Antiviral
DG03198 Anti-HCV agent
DG02000 HCV NS5B polymerase inhibitor
DG01886 Dasabuvir
D10553 Dasabuvir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
HCV NS5A/NS5B inhibitor
D10553 Dasabuvir (USAN/INN)
Drug groups [BR:br08330]
Antiviral
DG03198 Anti-HCV agent
DG02000 HCV NS5B polymerase inhibitor
DG01886 Dasabuvir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
HCV NS5A/NS5B inhibitor
DG01886 Dasabuvir
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 35
1 C8x C 9.7300 -13.9300
2 C8y C 9.7300 -12.5300
3 C8x C 10.9200 -11.8300
4 C8y C 12.1800 -12.5300
5 C8y C 12.1800 -13.9300
6 C8x C 10.9200 -14.6300
7 C8x C 13.3700 -11.8300
8 C8x C 14.5600 -12.5300
9 C8y C 14.5600 -13.9300
10 C8x C 13.3700 -14.6300
11 C8y C 15.7500 -14.6300
12 C8x C 16.9400 -13.9300
13 C8y C 18.2000 -14.6300
14 C8x C 18.2000 -16.0300
15 C8y C 17.0100 -16.7300
16 C8y C 15.7500 -16.0300
17 O2a O 14.5600 -16.7300
18 C1a C 13.3700 -16.0300
19 C1d C 17.0100 -18.1300
20 C1a C 17.0100 -19.5300
21 C1a C 18.4100 -18.1300
22 C1a C 15.6100 -18.1300
23 N4y N 19.3900 -13.9300
24 C8x C 19.3900 -12.5300
25 C8x C 20.6500 -11.8300
26 C8y C 21.8400 -12.5300
27 N4x N 21.8400 -13.9300
28 C8y C 20.6500 -14.6300
29 O5x O 23.0300 -11.8300
30 O5x O 20.6500 -16.0300
31 N1b N 8.5400 -11.8300
32 S4a S 7.3500 -12.5300
33 C1a C 6.1319 -11.8399
34 O3c O 6.6500 -13.7424
35 O3c O 8.0500 -13.7424
BOND 38
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 9 11 1
13 11 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 11 16 1
19 16 17 1
20 17 18 1
21 15 19 1
22 19 20 1
23 19 21 1
24 19 22 1
25 13 23 1
26 23 24 1
27 24 25 2
28 25 26 1
29 26 27 1
30 27 28 1
31 23 28 1
32 26 29 2
33 28 30 2
34 2 31 1
35 31 32 1
36 32 33 1
37 32 34 2
38 32 35 2
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