KEGG   DRUG: Verosudil
Entry
D10737                      Drug                                   
Name
Verosudil (USAN/INN)
Formula
C17H17N3O2S
Exact mass
327.1041
Mol weight
327.40
Structure
Simcomp
Remark
Chemical structure group: DG01867
Efficacy
Antiglaucoma, Rho-associated kinase inhibitor
Comment
Treatment of glaucoma
Target
ROCK [HSA:6093 9475] [KO:K04514 K17388]
  Pathway
hsa04270  Vascular smooth muscle contraction
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Serine/threonine kinases
   AGC group
    ROCK
     D10737  Verosudil (USAN/INN)
Other DBs
CAS: 1414854-42-4
PubChem: 254741698
LinkDB
KCF data

ATOM        23
            1   C8y C    18.0600  -13.7900
            2   C8x C    18.0600  -15.1900
            3   C8x C    19.2724  -15.8900
            4   C8y C    20.4849  -15.1900
            5   C8y C    20.4849  -13.7900
            6   C8x C    19.2724  -13.0900
            7   C8y C    21.6973  -15.8900
            8   N4x N    22.9097  -15.1900
            9   C8x C    22.9097  -13.7900
            10  C8x C    21.6973  -13.0900
            11  N1b N    16.8476  -13.0900
            12  C5a C    15.6351  -13.7900
            13  O5a O    15.6351  -15.1900
            14  C1c C    14.4227  -13.0900
            15  N1c N    13.2103  -13.7900
            16  C1a C    13.2103  -15.1900
            17  C1a C    11.9978  -13.0900
            18  C8y C    14.4227  -11.6900
            19  C8x C    15.5536  -10.8684
            20  C8x C    15.1216   -9.5390
            21  S2x S    13.7238   -9.5390
            22  C8x C    13.2918  -10.8684
            23  O5x O    21.6973  -17.2900
BOND        25
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    1  11 1
            13   11  12 1
            14   12  13 2
            15   12  14 1
            16   14  15 1
            17   15  16 1
            18   15  17 1
            19   14  18 1
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 1
            24   18  22 2
            25    7  23 2

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