KEGG   DRUG: ObiltoxaximabHelp
Entry
D10776                      Drug                                   

Name
Obiltoxaximab (USAN/INN);
Anthim (TN)
Product
Formula
C6444H9994N1734O2022S44
Exact mass
145430.0222
Mol weight
145519.5678
Sequence
(Heavy chain)
QVQLQQSGPE LKKPGASVKV SCKDSGYAFS SSWMNWVRQA PGQGLEWIGR IYPGDGDTNY
NGKFQGRVTI TADKSSSTAY MELSSLRSED TAVYFCARSG LLRYAMDYWG QGTLVTVSSA
STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG
LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKKVEPK SCDKTHTCPP CPAPELLGGP
SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS
TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL
TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ
QGNVFSCSVM HEALHNHYTQ KSLSLSPGK
(Light chain)
DIQMTQSPSS LSASVGDRVT ITCRASQDIR NYLNWYQQKP GKAVKLLIYY TSRLLPGVPS
RFSGSGSGTD YSLTISSQEQ EDIGTYFCQQ GNTLPWTFGQ GTKVEIRRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(dimer; disulfide bridges: H22-H96, H146-H202, H222-L214, H228-H'228, H231-H'231, H263-H323, H369-H427, H'22-H'96, H'146-H'202, H'222-L'214, H'263-H'323, H'369-H'427, L23-L88, L134-L194, L'23-L'88, L'134-L'194)
  Type
Peptide
Remark
ATC code: J06BB22
Product: D10776<US>
Efficacy
Anti-anthrax, Antitoxin
Comment
Monoclonal antibody
Treatment of exposure to Bacillus anthracis spores
Target
protective antigen (PA) [KO:K11030]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J06 IMMUNE SERA AND IMMUNOGLOBULINS
   J06B IMMUNOGLOBULINS
    J06BB Specific immunoglobulins
     J06BB22 Obiltoxaximab
      D10776  Obiltoxaximab (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D10776
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10776
BRITE hierarchy
Other DBs
CAS: 1351337-07-9
PubChem: 313046634
LinkDB All DBs

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