KEGG   DRUG: Nusinersen sodiumHelp
Entry
D10791                      Drug                                   

Name
Nusinersen sodium (JAN);
Spinraza (TN)
Formula
C234H323N61O128P17S17.17Na
Exact mass
7495.9693
Mol weight
7500.8854
Remark
Therapeutic category: 1190
ATC code: M09AX07
Chemical structure group: DG02002
Product (DG02002): D10881<US> D10791<JP>
Efficacy
Translation inhibitor
  Disease
Spinal muscular atrophy [DS:H00455]
Comment
Antisense oligonucleotide
Treatment of spinal muscular atrophy
Target
SMN2 [HSA:6607] [KO:K13129] (pre-mRNA intron7)
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M09 OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
   M09A OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
    M09AX Other drugs for disorders of the musculo-skeletal system
     M09AX07 Nusinersen
      D10791  Nusinersen sodium (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   119  Miscellaneous
    1190  Miscellaneous
     D10791  Nusinersen sodium (JAN)
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Signaling molecules
   Spliceosome
    SMN2
     D10791  Nusinersen sodium (JAN) <JP>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10791
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10791
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D10791
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10791
BRITE hierarchy
Other DBs
PubChem: 315431340
LinkDB All DBs

» Japanese version   » Back

DBGET integrated database retrieval system