KEGG   DRUG: Inotersen sodium
Entry
D10941                      Drug                                   

Name
Inotersen sodium (USAN);
Tegsedi (TN)
Product
Formula
C230H299N69O121P19S19. 19Na
Exact mass
7595.7129
Mol weight
7600.7669
Remark
ATC code: N07XX15
Chemical structure group: DG02693
Product (DG02693): D10941<US>
Efficacy
Neuroprotectant, Prealbumin expression inhibitor
  Disease
Hereditary transthyretin-mediated amyloidosis [DS:H00845]
Comment
Antisense oligonucleotide
Hereditary ATTR amyloidosis treatment
Target
TTR [HSA:7276] [KO:K20731] (mRNA)
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07X OTHER NERVOUS SYSTEM DRUGS
    N07XX Other nervous system drugs
     N07XX15 Inotersen
      D10941  Inotersen sodium (USAN) <US>
USP drug classification [BR:br08302]
 Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
  Inotersen
   D10941  Inotersen sodium (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Other transporters
   Others
    TTR
     D10941  Inotersen sodium (USAN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10941
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10941
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10941
Other DBs
CAS: 1432726-13-0
PubChem: 342581795
LinkDB

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