KEGG   Homo sapiens (human): 7276
Entry
7276              CDS       T01001                                 

Symbol
TTR, ATTR, CTS, CTS1, HEL111, HsT2651, PALB, TBPA, TTN
Name
(RefSeq) transthyretin
  KO
K20731  transthyretin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04918  Thyroid hormone synthesis
Disease
H00798  Familial carpal tunnel syndrome
H00845  Familial amyloidosis
Drug target
Acoramidis (DG03143): D11972 D11973
Inotersen (DG02693): D10940 D10941<US>
Patisiran (DG02955): D10794<JP/US> D11116
Tafamidis (DG01009): D09673<JP> D09674<JP/US>
Vutrisiran (DG03127): D11916 D11917
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    7276 (TTR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    7276 (TTR)
Transporters [BR:hsa02000]
 Other transporters
  Others
   7276 (TTR)
SSDB
Motif
Pfam: Transthyretin
Other DBs
NCBI-GeneID: 7276
NCBI-ProteinID: NP_000362
OMIM: 176300
HGNC: 12405
Ensembl: ENSG00000118271
Vega: OTTHUMG00000131984
Pharos: P02766(Tclin)
UniProt: P02766 E9KL36
Structure
LinkDB
Position
18:31591877..31598821
AA seq 147 aa
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
NT seq 444 nt   +upstreamnt  +downstreamnt
atggcttctcatcgtctgctcctcctctgccttgctggactggtatttgtgtctgaggct
ggccctacgggcaccggtgaatccaagtgtcctctgatggtcaaagttctagatgctgtc
cgaggcagtcctgccatcaatgtggccgtgcatgtgttcagaaaggctgctgatgacacc
tgggagccatttgcctctgggaaaaccagtgagtctggagagctgcatgggctcacaact
gaggaggaatttgtagaagggatatacaaagtggaaatagacaccaaatcttactggaag
gcacttggcatctccccattccatgagcatgcagaggtggtattcacagccaacgactcc
ggcccccgccgctacaccattgccgccctgctgagcccctactcctattccaccacggct
gtcgtcaccaatcccaaggaatga

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