KEGG   DRUG: Istiratumab
Entry
D10943                      Drug                                   
Name
Istiratumab (USAN/INN)
Efficacy
Antineoplastic
  Type
Bispecific antibody
Comment
Treatment of advanced solid tumors
Target
IGF1R (CD221) [HSA:3480] [KO:K05087]
ERBB3 (HER3) [HSA:2065] [KO:K05084]
  Pathway
hsa04010  MAPK signaling pathway
hsa04012  ErbB signaling pathway
hsa04151  PI3K-Akt signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor tyrosine kinases (RTK)
   EGFR family
    ERBB3 (HER3)
     D10943  Istiratumab (USAN/INN)
   INSR family
    IGF1R (CD221)
     D10943  Istiratumab (USAN/INN)
Other DBs
CAS: 1509928-04-4
PubChem: 350078324
LinkDB

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