K05084                      KO                                     

receptor tyrosine-protein kinase erbB-3 [EC:]
map01521  EGFR tyrosine kinase inhibitor resistance
map04010  MAPK signaling pathway
map04012  ErbB signaling pathway
map04020  Calcium signaling pathway
map04151  PI3K-Akt signaling pathway
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
H00408  Type 1 diabetes mellitus
H00865  Lethal congenital contractural syndrome
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
   04012 ErbB signaling pathway
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
   04020 Calcium signaling pathway
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
   04151 PI3K-Akt signaling pathway
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
   05205 Proteoglycans in cancer
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases  receptor protein-tyrosine kinase
     K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
HSA: 2065(ERBB3)
PTR: 451980(ERBB3)
PPS: 100974494(ERBB3)
GGO: 109025126(ERBB3)
PON: 100174431(ERBB3)
NLE: 100590102(ERBB3)
MCC: 711407(ERBB3)
MCF: 102115998(ERBB3)
CSAB: 103238504(ERBB3)
CATY: 105587314(ERBB3)
PANU: 101003778(ERBB3)
RRO: 104673694(ERBB3)
RBB: 108515999(ERBB3)
TFN: 117089952(ERBB3)
PTEH: 111541863(ERBB3)
CJC: 100409758(ERBB3)
SBQ: 101030064(ERBB3)
MMUR: 105865027(ERBB3)
MMU: 13867(Erbb3)
MCAL: 110302668(Erbb3)
MPAH: 110326297(Erbb3)
RNO: 29496(Erbb3)
MCOC: 116076169(Erbb3)
MUN: 110559383(Erbb3)
CGE: 100767681(Erbb3)
PLEU: 114681754(Erbb3)
NGI: 103746501(Erbb3)
HGL: 101721671(Erbb3)
CCAN: 109686062(Erbb3)
OCU: 100008807(ERBB3)
OPI: 101517747(ERBB3)
TUP: 102468023(ERBB3)
CFA: 481105(ERBB3)
VVP: 112922396(ERBB3)
VLG: 121490972(ERBB3)
AML: 100468735(ERBB3)
UMR: 103656927(ERBB3)
UAH: 113256440(ERBB3)
ORO: 101385903(ERBB3)
ELK: 111160180
MPUF: 101680042(ERBB3)
EJU: 114215065(ERBB3)
MLX: 118008728(ERBB3)
FCA: 101085388(ERBB3)
PYU: 121040944(ERBB3)
PBG: 122473747(ERBB3)
PTG: 102948909(ERBB3)
PPAD: 109270315(ERBB3)
AJU: 106986858(ERBB3)
HHV: 120219930(ERBB3)
BTA: 785655(ERBB3)
BOM: 102273820(ERBB3)
BIU: 109559378(ERBB3)
BBUB: 102395621(ERBB3)
CHX: 102173448(ERBB3)
OAS: 101103889(ERBB3)
ODA: 120857431(ERBB3)
CCAD: 122427060(ERBB3)
SSC: 100525045(ERBB3)
CFR: 102506629(ERBB3)
CBAI: 105075904(ERBB3)
CDK: 105086379(ERBB3)
BACU: 103015964(ERBB3)
LVE: 103087241(ERBB3)
OOR: 101288152(ERBB3)
DLE: 111173887(ERBB3)
PCAD: 102975550(ERBB3)
ECB: 100059216(ERBB3)
EPZ: 103557568(ERBB3)
EAI: 106832936(ERBB3)
MYB: 102248465(ERBB3)
MYD: 102774755(ERBB3)
MMYO: 118650120(ERBB3)
MNA: 107546211(ERBB3)
PKL: 118728255(ERBB3)
HAI: 109396911(ERBB3)
DRO: 112319025(ERBB3)
SHON: 118976014(ERBB3)
AJM: 119048554(ERBB3)
MMF: 118624257(ERBB3)
PALE: 102895392(ERBB3)
PGIG: 120604897(ERBB3)
RAY: 107521255(ERBB3)
MJV: 108398133(ERBB3)
TOD: 119248041(ERBB3)
LAV: 100668973(ERBB3)
TMU: 101354434
MDO: 100028072 100028103(ERBB3)
SHR: 100924586
PCW: 110210914
OAA: 100079793(ERBB3)
GGA: 693245(ERBB3)
PCOC: 116239283(ERBB3)
CJO: 107325755(ERBB3)
NMEL: 110389140(ERBB3)
ACYG: 106029359
TGU: 115491473(ERBB3)
LSR: 110482393(ERBB3)
PMOA: 120505872(ERBB3)
PHI: 102101993(ERBB3)
ETL: 114070808(ERBB3)
FPG: 101914106(ERBB3)
FCH: 102056537
NNI: 104017527(ERBB3)
ASN: 102376821(ERBB3)
AMJ: 102577159(ERBB3)
PSS: 102454909(ERBB3)
CPIC: 101942522(ERBB3)
TST: 117888990(ERBB3)
CABI: 116827815(ERBB3)
ACS: 100556326(erbb3)
PVT: 110073465(ERBB3)
PBI: 103051488(ERBB3)
PMUR: 107284855(ERBB3)
TSR: 106555502(ERBB3)
PGUT: 117662893(ERBB3)
PMUA: 114587816(ERBB3)
ZVI: 118079615(ERBB3)
GJA: 107108277(ERBB3)
XLA: 108708565(erbb3.L) 108709833(erbb3.S)
XTR: 100493384(erbb3)
NPR: 108790515(ERBB3)
DRE: 100149258 386635(erbb3a) 544664(erbb3b)
CCAR: 109104287
IPU: 108271615 108276025(erbb3)
PHYP: 113527462(erbb3) 113530351
AMEX: 103028053(erbb3) 103032103
EEE: 113581376 113581542(erbb3)
TRU: 101061551 101069394(erbb3)
LCO: 104932439 104938399(erbb3)
NCC: 104941411(erbb3) 104956941
CGOB: 115008140(erbb3) 115010612
ELY: 117257063(erbb3a) 117257630(erbb3b)
PLEP: 121947136(erbb3b) 121955848(erbb3a)
SLUC: 116038790(erbb3b) 116041689(erbb3a)
ECRA: 117944075(erbb3a) 117947750(erbb3b)
PFLV: 114554019(erbb3) 114559209
GAT: 120829080(erbb3b) 120835587(erbb3a)
PPUG: 119194240(erbb3a) 119199286
MSAM: 119886809(erbb3a) 119906034(erbb3b)
CUD: 121507170(erbb3a) 121518167(erbb3b)
OAU: 116325811(erbb3b) 116333795
OLA: 101172402(erbb3) 101172978
OML: 112144829 112159600(erbb3b)
XMA: 102225708 102230188(erbb3)
XHE: 116710979(erbb3) 116727336
PRET: 103465260(erbb3) 103467364
CVG: 107082131(erbb3) 107092166
CTUL: 119776657(erbb3a) 119785035(erbb3b)
NFU: 107385695(erbb3) 107390894
KMR: 108235300(erbb3b) 108235724(erbb3a)
ALIM: 106518025(erbb3) 106536334
LCF: 108876575 108881471(erbb3)
SDU: 111219064 111221725(erbb3)
SLAL: 111667812(erbb3) 111668898
XGL: 120783170(erbb3a) 120803750(erbb3b)
HCQ: 109522344(erbb3) 109531391
BPEC: 110164957 110168364(erbb3)
MALB: 109964444(erbb3) 109971109
PKI: 111854164(erbb3)
LOC: 102684317(erbb3)
PSPA: 121309044(erbb3a)
LCM: 102353616(ERBB3)
 » show all
Kraus MH, Issing W, Miki T, Popescu NC, Aaronson SA
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.
Proc Natl Acad Sci U S A 86:9193-7 (1989)

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