KEGG   DRUG: RevefenacinHelp
Entry
D10978                      Drug                                   

Name
Revefenacin (USAN/INN)
Product
Formula
C35H43N5O4
Exact mass
597.3315
Mol weight
597.747
Structure
Mol fileKCF fileDB search
Remark
Product: D10978<US>
Efficacy
Antiasthmatic, Muscarinic acetylcholine receptor antagonist
Comment
Treatment of chronic obstructive pulmonary disease
Target
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D10978  Revefenacin (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10978
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10978
BRITE hierarchy
Other DBs
CAS: 864750-70-9
PubChem: 342581822
ChEMBL: CHEMBL3833319
LinkDB All DBs
KCF data Show

ATOM        44
            1   C8x C    11.5500  -10.5000
            2   C8x C    11.5500  -11.9000
            3   C8y C    12.7624  -12.6000
            4   C8x C    13.9749  -11.9000
            5   C8x C    13.9749  -10.5000
            6   C8x C    12.7624   -9.8000
            7   C8y C    12.7624  -13.9998
            8   C8x C    11.5332  -14.7097
            9   C8x C    11.5334  -16.1097
            10  C8x C    12.7459  -16.8096
            11  C8x C    13.9751  -16.0997
            12  C8y C    13.9749  -14.6997
            13  N1b N    15.2124  -14.0000
            14  C7a C    16.4249  -14.7000
            15  O7a O    17.6373  -14.0000
            16  C1y C    18.8497  -14.7000
            17  C1x C    18.8497  -16.0999
            18  C1x C    20.0622  -16.7999
            19  N1y N    21.2746  -16.0999
            20  C1x C    21.2746  -14.7000
            21  C1x C    20.0622  -14.0000
            22  C1b C    22.4911  -16.8022
            23  C1b C    23.6886  -16.1107
            24  N1c N    23.6886  -14.7107
            25  C5a C    24.8839  -14.0202
            26  C8y C    26.0623  -14.7002
            27  C8x C    26.0627  -16.0998
            28  C8x C    27.2753  -16.7995
            29  C8y C    28.4875  -16.0992
            30  C8x C    28.4872  -14.6996
            31  C8x C    27.2746  -13.9999
            32  C1b C    29.7023  -16.8002
            33  N1y N    30.8978  -16.1094
            34  C1x C    32.0855  -16.7947
            35  C1x C    33.2977  -16.0944
            36  C1y C    33.2974  -14.6944
            37  C1x C    32.1097  -14.0091
            38  C1x C    30.8974  -14.7094
            39  C5a C    34.5240  -13.9855
            40  N1a N    35.7323  -14.6826
            41  O5a O    34.5233  -12.6001
            42  O5a O    24.8840  -12.6004
            43  C1a C    22.4500  -13.9957
            44  O6a O    16.4249  -16.0998
BOND        48
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     3   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13    7  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   16  21 1
            24   19  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   29  30 1
            33   30  31 2
            34   26  31 1
            35   29  32 1
            36   32  33 1
            37   33  34 1
            38   34  35 1
            39   35  36 1
            40   36  37 1
            41   37  38 1
            42   33  38 1
            43   36  39 1
            44   39  40 1
            45   39  41 2
            46   25  42 2
            47   24  43 1
            48   14  44 2

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