KEGG   DRUG: Vestronidase alfa
Entry
D11004                      Drug                                   
Name
Vestronidase alfa (USAN/INN);
Vestronidase alfa (genetical recombination) (JAN);
Vestronidase alfa-vjbk;
MepseVII (TN)
Product
Remark
Therapeutic category: 3959
ATC code: A16AB18
Product: D11004<JP/US>
Efficacy
Lysosomal storage disease treatment, Enzyme replacement (beta-glucuronidase)
  Disease
Mucopolysaccharidosis VII; Sly syndrome [DS:H00132]
  Type
Enzyme replacement therapy product
Target
GUSB* [HSA_VAR:2990v1] [HSA:2990] [KO:K01195]
  Pathway
hsa04142  Lysosome
  Network
nt06012  Glycosaminoglycan degradation
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AB Enzymes
     A16AB18 Vestronidase alfa
      D11004  Vestronidase alfa (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
  Vestronidase Alfa
   D11004  Vestronidase alfa (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   395  Enzyme preparations
    3959  Others
     D11004  Vestronidase alfa (USAN/INN); Vestronidase alfa (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Glycosidases
    GUSB* [HSA_VAR:2990v1]
     D11004  Vestronidase alfa (USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11004
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11004
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D11004
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11004
Pharmacogenomic biomarkers [br08341.html]
 Germline mutations in genetic disorder treatments
  D11004
Other DBs
CAS: 1638194-78-1
PubChem: 342581841
LinkDB

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