KEGG   DRUG: Voretigene neparvovecHelp
Entry
D11008                      Drug                                   

Name
Voretigene neparvovec (USAN/INN);
Voretigene neparvovec-rzyl;
Luxturna (TN)
Product
Remark
Product: D11008<US>
Efficacy
Vision loss treatment
  Disease
Retinal dystrophy (biallelic RPE65 mutated) [DS:H00527 H00837]
Comment
Gene therapy product
Adeno-associated virus serotype 2 (AAV2) vector carrying a functional copy of the RPE65 gene into the retinal pigment epithelial (RPE) cells
Target
RPE65 [HSA:6121] [KO:K11158]
  Pathway
hsa00830  Retinol metabolism
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Carboxylic-ester hydrolases
    RPE65
     D11008  Voretigene neparvovec (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 Cellular and gene therapy products
  D11008
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11008
BRITE hierarchy
Other DBs
CAS: 1646819-03-5
PubChem: 342581844
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