KEGG   DRUG: Ropeginterferon alfa-2b
Entry
D11027                      Drug                                   
Name
Ropeginterferon alfa-2b (INN);
Ropeginterferon alfa-2b (genetical recombination) (JAN);
Ropeginterferon alfa-2b-njft;
Besremi (TN)
Product
BESREMI (PharmaEssentia USA)
Sequence
PCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM
IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV
RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE
(Disulfide bridge: 2-99, 30-139)
  Type
Peptide
Class
Immunological agent
 DG01752  Interferone
Remark
ATC code: L03AB15
Product: D11027<US>
Efficacy
Antineoplastic, Antiviral
  Disease
Polycythemia vera [DS:H00012]
Target
IFNAR1 [HSA:3454] [KO:K05130]
IFNAR2 [HSA:3455] [KO:K05131]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04620  Toll-like receptor signaling pathway
hsa04630  JAK-STAT signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB15 Ropeginterferon alfa-2b
      D11027  Ropeginterferon alfa-2b (INN) <US>
USP drug classification [BR:br08302]
 Immunological Agents
  Immunostimulants
   Interferons
    Ropeginterferon Alfa-2b
     D11027  Ropeginterferon alfa-2b (INN)
Drug groups [BR:br08330]
 Immunological agent
  DG01752  Interferone
   D11027  Ropeginterferon alfa-2b
Drug classes [BR:br08332]
 Immunological agent
  DG01752  Interferone
   D11027  Ropeginterferon alfa-2b
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interferon receptors
    IFNAR1
     D11027  Ropeginterferon alfa-2b (INN) <US>
    IFNAR2
     D11027  Ropeginterferon alfa-2b (INN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11027
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11027
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11027
Other DBs
CAS: 1335098-50-4
PubChem: 350078346
LinkDB

» Japanese version   » Back

DBGET integrated database retrieval system