| Entry |
|
|---|
| Name |
Savolitinib (JAN/USAN/INN) |
|---|
| Formula |
C17H15N9
|
|---|
| Exact mass |
345.1450
|
|---|
| Mol weight |
345.36
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
|---|
| Comment |
Treatment of cancer
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01E PROTEIN KINASE INHIBITORS
L01EP Cellular-mesenchymal-epithelial transition factor (c-MET) kinase inhibitors
L01EP03 Savolitinib
D11139 Savolitinib (JAN/USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
D11139 Savolitinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
MET family
MET
D11139 Savolitinib (JAN/USAN/INN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C8y C 13.8600 -18.9000
2 C8x C 13.8600 -20.3000
3 N5x N 15.0724 -21.0000
4 C8y C 16.2849 -20.3000
5 C8y C 16.2849 -18.9000
6 N5x N 15.0724 -18.2000
7 N5x N 17.6164 -20.7326
8 N5x N 18.4393 -19.6000
9 N4y N 17.6164 -18.4674
10 C1c C 18.0475 -17.1406
11 C8y C 19.4269 -16.8474
12 C8x C 20.3895 -17.9169
13 N4y N 21.7590 -17.6261
14 C8y C 22.1918 -16.2947
15 C8x C 21.2293 -15.2252
16 C8x C 19.8598 -15.5160
17 C8x C 22.8914 -18.4492
18 C8x C 24.0242 -17.6265
19 N5x N 23.5919 -16.2950
20 C8y C 12.6476 -18.2000
21 C8x C 12.5015 -16.8102
22 N5x N 11.1346 -16.5196
23 N4y N 10.4358 -17.7298
24 C8x C 11.3709 -18.7684
25 C1a C 9.0399 -17.8765
26 C1a C 17.1211 -16.1115
BOND 30
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 2
9 8 9 1
10 5 9 1
11 9 10 1
12 10 11 1
13 11 12 2
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 2
18 11 16 1
19 13 17 1
20 17 18 2
21 18 19 1
22 14 19 2
23 1 20 1
24 20 21 1
25 21 22 2
26 22 23 1
27 23 24 1
28 20 24 2
29 23 25 1
30 10 26 1 #Up
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