KEGG   DRUG: Vosoritide
Entry
D11190                      Drug                                   

Name
Vosoritide (USAN/INN);
Vosoritide (genetical recombination) (JAN);
Voxzogo (TN)
Formula
C176H290N56O51S3
Exact mass
4100.0983
Mol weight
4102.7254
Sequence
PGQEHPNARK YKGANKKGLS KGCFGLKLDR IGSMSGLGC
(Disulfide bridge: 23-39)
  Type
Peptide
Efficacy
Achondroplasia therapeutic agent
Comment
Treatment of Achondroplasia
modified recombinant human C-type natriuretic peptide (CNP)
Target
NPR2 [HSA:4882] [KO:K12324]
  Pathway
hsa04022  cGMP-PKG signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases (EC4)
   Phosphorus-oxygen lyases
    NPR2
     D11190  Vosoritide (USAN/INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11190
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11190
Other DBs
CAS: 1480724-61-5
PubChem: 384585169
LinkDB

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