KEGG   DRUG: Apimostinel
Entry
D11299                      Drug                                   

Name
Apimostinel (USAN)
Formula
C25H37N5O6
Exact mass
503.2744
Mol weight
503.5912
Structure
Efficacy
Antidepressant, NMDA receptor modulator
Comment
Treatment of major depression disorder
Target
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), NMDA
    GRIN (NMDAR)
     D11299  Apimostinel (USAN)
Other DBs
CAS: 1421866-48-9
PubChem: 384585277
ChEMBL: CHEMBL3989872
LinkDB
KCF data

ATOM        36
            1   C5a C    14.2800  -20.1600
            2   N1y N    15.4700  -20.8600
            3   C1y C    13.0900  -20.8600
            4   O5a O    14.2800  -18.7600
            5   C1x C    15.9600  -22.1900
            6   C1x C    17.3600  -22.1900
            7   C1x C    17.7800  -20.8600
            8   C1z C    16.5900  -20.0200
            9   N1y N    11.9000  -20.0900
            10  C1x C    10.8500  -20.9300
            11  C1x C    11.2700  -22.1900
            12  C1x C    12.6700  -22.1900
            13  C5a C    11.9000  -18.6900
            14  C1c C    10.6400  -18.0600
            15  O5a O    13.0900  -17.9200
            16  C1c C     9.4500  -18.7600
            17  C1b C    17.7800  -19.3200
            18  N1a N    10.6624  -16.6608
            19  C1a C     8.2319  -18.0699
            20  O1a O     9.4614  -20.1600
            21  C5a C    16.5900  -18.6200
            22  C8y C    18.9981  -20.0101
            23  O5a O    15.3776  -17.9200
            24  C8x C    18.9397  -21.4194
            25  C8x C    20.2279  -22.1094
            26  C8x C    21.4345  -21.3994
            27  C8x C    21.4229  -19.9901
            28  C8x C    20.2047  -19.3001
            29  N1b N    17.8024  -17.9200
            30  C1c C    17.8024  -16.5200
            31  C1c C    18.9979  -15.8296
            32  C1a C    20.2104  -16.5296
            33  C5a C    16.5733  -15.8102
            34  N1a N    15.3693  -16.5054
            35  O5a O    16.5734  -14.4201
            36  O1a O    18.9980  -14.4203
BOND        38
            1     1   2 1
            2     3   1 1 #Down
            3     1   4 2
            4     2   5 1
            5     5   6 1
            6     6   7 1
            7     7   8 1
            8     2   8 1
            9     3   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    3  12 1
            14    9  13 1
            15   13  14 1
            16   13  15 2
            17   14  16 1
            18    8  17 1 #Up
            19   14  18 1 #Down
            20   16  19 1
            21   16  20 1 #Down
            22    8  21 1 #Down
            23   17  22 1
            24   21  23 2
            25   22  24 2
            26   24  25 1
            27   25  26 2
            28   26  27 1
            29   27  28 2
            30   22  28 1
            31   21  29 1
            32   29  30 1
            33   30  31 1
            34   31  32 1
            35   30  33 1 #Down
            36   33  34 1
            37   33  35 2
            38   31  36 1 #Down

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