| Entry |
|
|---|
| Name |
Apimostinel (USAN) |
|---|
| Formula |
C25H37N5O6
|
|---|
| Exact mass |
503.2744
|
|---|
| Mol weight |
503.59
|
|---|
| Structure |
|
|---|
| Efficacy |
Antidepressant, NMDA receptor modulator |
|---|
| Comment |
Treatment of major depression disorder
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN (NMDAR)
D11299 Apimostinel (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 36
1 C5a C 14.2800 -20.1600
2 N1y N 15.4700 -20.8600
3 C1y C 13.0900 -20.8600
4 O5a O 14.2800 -18.7600
5 C1x C 15.9600 -22.1900
6 C1x C 17.3600 -22.1900
7 C1x C 17.7800 -20.8600
8 C1z C 16.5900 -20.0200
9 N1y N 11.9000 -20.0900
10 C1x C 10.8500 -20.9300
11 C1x C 11.2700 -22.1900
12 C1x C 12.6700 -22.1900
13 C5a C 11.9000 -18.6900
14 C1c C 10.6400 -18.0600
15 O5a O 13.0900 -17.9200
16 C1c C 9.4500 -18.7600
17 C1b C 17.7800 -19.3200
18 N1a N 10.6624 -16.6608
19 C1a C 8.2319 -18.0699
20 O1a O 9.4614 -20.1600
21 C5a C 16.5900 -18.6200
22 C8y C 18.9981 -20.0101
23 O5a O 15.3776 -17.9200
24 C8x C 18.9397 -21.4194
25 C8x C 20.2279 -22.1094
26 C8x C 21.4345 -21.3994
27 C8x C 21.4229 -19.9901
28 C8x C 20.2047 -19.3001
29 N1b N 17.8024 -17.9200
30 C1c C 17.8024 -16.5200
31 C1c C 18.9979 -15.8296
32 C1a C 20.2104 -16.5296
33 C5a C 16.5733 -15.8102
34 N1a N 15.3693 -16.5054
35 O5a O 16.5734 -14.4201
36 O1a O 18.9980 -14.4203
BOND 38
1 1 2 1
2 3 1 1 #Down
3 1 4 2
4 2 5 1
5 5 6 1
6 6 7 1
7 7 8 1
8 2 8 1
9 3 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 3 12 1
14 9 13 1
15 13 14 1
16 13 15 2
17 14 16 1
18 8 17 1 #Up
19 14 18 1 #Down
20 16 19 1
21 16 20 1 #Down
22 8 21 1 #Down
23 17 22 1
24 21 23 2
25 22 24 2
26 24 25 1
27 25 26 2
28 26 27 1
29 27 28 2
30 22 28 1
31 21 29 1
32 29 30 1
33 30 31 1
34 31 32 1
35 30 33 1 #Down
36 33 34 1
37 33 35 2
38 31 36 1 #Down
|
|---|
