KEGG   DRUG: Benzhydrocodone and acetaminophen
Entry
D11628            Mixture   Drug                                   
Name
Benzhydrocodone and acetaminophen;
Apadaz (TN)
Product
APADAZ (Zevra Therapeutics)
Component
Acetaminophen [DR:D00217], (Benzhydrocodone hydrochloride [DR:D10692] | Benzhydrocodone [DR:D10612])
Class
Metabolizing enzyme substrate
 DG01644  CYP2D6 substrate
 DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate
Remark
Product: D11628<US>
Efficacy
Analgesic
Comment
Management of acute pain severe enough to require an opioid analgesic
Metabolism
Enzyme: CYP2D6 [HSA:1565], CYP3A4 [HSA:1576]
Interaction
Brite
USP drug classification [BR:br08302]
 Analgesics
  Analgesics Combinations/ Other
   Acetaminophen/ Benzhydrocodone Hydrochloride
    D11628  Benzhydrocodone and acetaminophen
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG01644  CYP2D6 substrate
   D11628  Benzhydrocodone and acetaminophen
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D11628  Benzhydrocodone and acetaminophen
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D11628
Other DBs
PubChem: 405226495
LinkDB

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