| Entry |
|
|---|
| Name |
Mevidalen (USAN) |
|---|
| Formula |
C24H29Cl2NO3
|
|---|
| Exact mass |
449.1524
|
|---|
| Mol weight |
450.39
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiparkinsonian, Dementia therapeutic agent, Dopamine receptor agonist |
|---|
| Comment |
Treatment of Parkinson's disease and Alzheimer's disease
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D11826 Mevidalen (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 30
1 C8x C 15.0543 -14.6357
2 C8x C 15.0543 -16.0372
3 C8x C 16.2455 -16.7379
4 C8y C 17.5068 -16.0372
5 C8y C 17.5068 -14.6357
6 C8y C 16.2455 -13.9350
7 C1b C 16.2455 -12.5336
8 C1b C 15.0543 -11.8329
9 C1d C 13.8631 -12.5336
10 O1a O 12.6018 -13.2343
11 C1a C 13.1624 -11.3424
12 C1a C 14.5638 -13.7248
13 C1y C 18.6980 -16.7379
14 N1y N 19.8893 -16.0372
15 C1y C 19.8893 -14.6357
16 C1x C 18.6980 -13.9350
17 C1b C 21.1506 -13.9350
18 O1a O 22.3418 -14.6357
19 C5a C 21.1506 -16.7379
20 O5a O 22.3418 -16.0372
21 C1b C 21.1506 -18.1393
22 C8y C 22.3418 -18.8401
23 C8y C 22.3418 -20.2415
24 C8x C 23.5330 -20.9422
25 C8x C 24.7242 -20.2415
26 C8x C 24.7242 -18.8401
27 C8y C 23.5330 -18.1393
28 C1a C 18.6980 -18.1393
29 X Cl 21.0805 -21.0123
30 X Cl 23.5330 -16.7379
BOND 32
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 6 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 9 11 1
12 9 12 1
13 4 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 5 16 1
18 15 17 1 #Down
19 17 18 1
20 14 19 1
21 19 20 2
22 19 21 1
23 21 22 1
24 22 23 2
25 23 24 1
26 24 25 2
27 25 26 1
28 26 27 2
29 22 27 1
30 13 28 1 #Up
31 23 29 1
32 27 30 1
|
|---|
